Hypersensitivity (Allergy)

11/01/2000 - "4) Skin test and/or IgE RAST showed positive results in most cases, suggesting that the response itself is linked to type I allergic reaction. "
11/01/2010 - "In conclusion, it can be stated that 'new' allergies can suddenly arise, there are allergen-specific risk groups, local IgE-production is also possible in the CNS, allergen avoidance can be very effective in terms of primary prevention, sensitization spreading can be made reversible by effective prevention, and finally, certain allergies can luckily become history within a relatively short period of time. "
11/01/1990 - "Sera from 33 patients with mold allergy proven by bronchial provocation were analyzed for specific IgE against six mold species comparing an improved Phadebas RAST with four other techniques. "
01/01/2011 - "These results show that this rapid test for the measurement of total tear IgE is easy to perform on an outpatient basis and may be helpful in the management of ocular allergy."
10/01/2003 - "There is good concurrence between skin testing techniques and various serum measures of specific IgE, and both methods can be used effectively for screening inhalant allergy, although per-test costs for in vitro methods remain higher than comparable costs for skin testing [28]. "

02/01/2003 - "To evaluate the safety and efficacy of oral desensitization in patients with allergy induced by the most common food allergens. "
09/01/2012 - "The development of a new methodology combining the so-called allergenic molecule-based diagnosis with the multiplex microarray technology and allowing the analysis of multiple purified allergens in a single test represents an important improvement in allergy diagnosis. "
01/01/2011 - "In conclusion, the specific, accurate and reproducible quantification of three important carrot allergens may help to identify less allergenic carrot varieties, as well as to standardize the amount of allergens in extracts used for carrot allergy diagnosis."
01/01/2000 - "In our opinion, the results of SPT should be very carefully examined, when diagnosing occupational allergy, as in some apprentice bakers positive results of SPT to flour allergens are found before vocational training. "
01/01/2005 - "The study results confirm that skin prick tests to common allergens, particularly to moulds, should be performed in bakers before starting occupational exposure and subjects with positive results should be considered as a group of high risk of occupational allergy."

08/01/1991 - "Moreover, CV generated delayed-type hypersensitivity to salmonella antigens and also conferred complete protection against 500 LD50 challenge of S. "
09/01/2015 - "OM-X® is also known to have beneficial health properties, and some of its components show effects on antigen (Ag)-stimulated degranulation activity, indicating that OM-X® may be useful in the treatment of allergy responses and symptoms. "
08/01/1994 - "However, the delayed-type hypersensitivity responses to parasite antigens were significantly greater in resistant lambs than those in random-bred lambs. "
12/01/1986 - "Dermal hypersensitivity, measured by changes in double skin thickness, was significantly greater in nonpregnant heifers to porin (P less than 0.01) and group 3 (P less than 0.05) antigens at 24 h post-injection, but no significant differences in skin thicknesses or in the nature of the lesions were observed at 48 h. "
09/01/2001 - "Additionally, delayed-type hypersensitivity response to recall antigens improved preoperatively and remained better until hospital discharge. "

01/01/2010 - "SCIT is the only and a very effective treatment for insect venom allergy. "
04/01/2006 - "The availability of recombinant Api m 3 provides a tool for both the development of improved diagnostic tests and the design of safer and more effective immunotherapeutic approaches for honeybee venom allergy. "
03/01/2000 - "The findings of this meta-analysis support the conclusion that SIT is effective in the treatment of Hymenoptera venom hypersensitivity."
03/01/1989 - "The epidemiology and natural history of insect venom allergy is emerging in the past decade and has clarified the reasons for the false perceptions that whole body extracts of the insects were considered effective for therapy. "
06/01/2011 - "VIT with 50 μg maintenance dose lasting 5 yr appears to be safe and effective enough to induce tolerance in children with hymenoptera venom hypersensitivity."

01/01/1989 - "The autolyzates induce the production of specific antibodies, the delayed type of hypersensitivity, and some degree of protection against European virulent strain 130. "
09/15/2014 - "Out of the 116 trials analyzed for the dose-immune response relationship, we found a statistically significant dose-immune response correlation only when the immune response was measured by antibodies (P < 0.001) or delayed type hypersensitivity (P < 0.05). "
07/01/2011 - "This is contrary to what was proposed in a number of other studies using neutralizing and activating antibodies and questions the clinical relevance of Tim1 and Tim3 for novel allergy therapies."
05/01/2011 - "In summary, the Phl p 5-specific antibodies are the first full set of allergy-related antibody isotypes of their kind and represent valuable tools for studies of fundamental mechanisms and structure/function relationships in allergy."
01/01/2010 - "In this study we aimed to investigate the possible involvement of drug- and/or metabolite-specific antibodies in selective DF hypersensitivity. "

09/01/2008 - "This information is being applied to the design and production of allergy vaccines, some of which already have proven efficacy and safety in clinical trials."
01/01/2015 - "The new findings are important for understanding basic disease-causing mechanisms at the cellular level, which ultimately may pave the way for instigating novel approaches for targeted desensitization strategies and improved allergy vaccines. "
06/01/2012 - "Successful clinical trials performed with the new vaccines indicate that broad allergy vaccination is on the horizon and may help to control the allergy pandemic."
09/15/2003 - "Specific allergy vaccination is an efficient treatment for allergic disease; however, the development of safer vaccines would enable a more general use of the treatment. "
06/01/2012 - "Vaccines aim to establish or strengthen immune responses but are also effective for the treatment of allergy. "

09/01/1981 - "These results support the position that testing with PPL, PA, and Pen G is a rapid, safe, and effective method for identifying patients at risk, or not at risk, for allergic reactions to penicillin."
01/01/2015 - "While the gold standard for diagnosing penicillin allergy is challenge, it is not recommended that this be done without first carrying out diagnostic skin testing. "
11/01/2014 - "Overall, improved referral to an allergist will help to identify patients who have penicillin allergy requiring avoidance. "
11/01/2010 - "Certain points must be improved though: time of the sampling, antibiotic therapy in case of quick delivery, management of patients with allergy to penicillin. "
01/01/2000 - "These agents are effective against gram-negative rods and anaerobes, reach therapeutic levels rapidly after parenteral administration, and, in the absence of penicillin allergy, generally exhibit low toxicity. "

02/01/2007 - "IgG4 have been reported as blocking antibody and the protective effects of blocking antibody may be clear in inhalant allergy. "
05/01/2004 - "We show that RA-specific IgG isotype ASC numbers are very useful and sensitive parameters to identify drug-induced hypersensitivity in both PLN and ALN. "
03/01/2002 - "The aim of this study was to investigate the effects of maternal immunization with Dermatophagoides pteronyssinus (Dp) on the hypersensitivity response and IgG subclass production in offspring using a murine model. "
04/01/2000 - "Further studies with oral IgG challenges should be performed to document the conclusion that in vitro reactivity correlates with clinical hypersensitivity. "
01/01/2016 - "Seasonal allergies and serial changes of serum levels of IgG4 in cases treated with maintenance therapy for IgG4-related disease."

02/01/2001 - "Results from many laboratories have generated guarded optimism that DNA-based immunotherapeutics may be effective for the reversal of allergic hypersensitivity states in humans, and several clinical trials have already been initiated. "
08/01/2000 - "The present series of experiments demonstrate that both gene vaccination and coimmunization with protein and immunostimulatory DNA are effective in attenuating the development of anaphylactic hypersensitivity in subsequently T(H2) sensitized mice."
03/01/2009 - "Our results indicate that the administration of NLX as an adjuvant increased the ability of the gD1 DNA vaccine to enhance cytolytic T lymphocyte activity, lymphocyte proliferation, delayed-type hypersensitivity and shifting the immune response toward a T helper (Th)1 pattern and improved protective immunity against HSV-1. "
02/01/2014 - "He was diagnosed with drug-induced hypersensitivity syndrome (DIHS) based on positive results in the human herpesvirus (HHV)-6 DNA test, an indicator of HHV-6 reactivation. "
09/01/2013 - "Is electroporation decisive for the efficacy of DNA vaccine against house dust mite allergy?"

12/01/2013 - "This study was conducted to assess the efficacy of a commercially available novel herbal dentifrice in reduction of dentinal hypersensitivity. "
01/01/2008 - "Dentinal hypersensitivity: a 12-week study of a novel dentifrice delivery system comparing different brushing times and assessing the efficacy for hard-to-reach molar teeth."
08/01/2003 - "Anticaries efficacy of a new dentifrice for hypersensitivity."
12/01/2013 - "Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial."
12/01/2012 - "Comparison of efficacy of three commercially available dentifrices [corrected] on dentinal hypersensitivity: a randomized clinical trial."

07/01/2011 - "The clinical efficacy of the most common routes, subcutaneous (SCIT) and sublingual (SLIT) immunotherapy, is documented for respiratory allergy by double-blind, placebo-controlled, randomised clinical trials (DB PC RCT). "
04/01/2015 - "The molecular epidemiology approach in veterinary allergy management, by the characterization of individual patients' allergoms and by choosing the best molecular allergen pool for each patient could also improve the efficacy of allergy immunotherapy."
05/01/2014 - "Concerning respiratory allergy, CRD is considered useful in investigating cross-reactivity and in defining the best treatment option, even if only 32% of patients treated with immunotherapy had been previously studied with CRD. "
08/01/2011 - "The assessment of clinical efficacy of immunotherapy in patients with respiratory allergy is highly affected by variability and lack of validated outcome measures such as symptom and medication scores. "
09/01/2012 - "Subcutaneous specific immunotherapy (SCIT) has proven sustained clinical efficacy against allergy. "

01/01/1990 - "When IFN-gamma injections were given during the contact allergic reaction there was no significant reduction of ear swelling until 72 h (p less than 0.01). "
11/01/2001 - "A major potential benefit provided by MPL adjuvant is the promotion of a Th1 response which enhances the efficacy of allergy vaccination and can consequently allow a reduction in the number of injections required for treatment. "
06/01/2004 - "There are a variety of prevention strategies that could be implemented to reduce or eliminate this risk, such as improved nurse training in the administration of allergy injections and compliance with the recommendations in the "Allergen Immunotherapy: A Practice Parameter" for use of patient-specific vials, standardized dosage sheets, and implementation of triple-checking of identity to make sure the correct patient is receiving the correct injection."
11/01/1996 - "The readings, taken 20 minutes after the intradermic injections, with positive results were considered as hypersensitivity of the immediate type. "
03/01/2011 - "In the study of adjuvant effect in TCM injections + OVA (at the dose level that doesn't cause allergic reactions), the PCA results of SHL and YXC were positive and there was a increase in content of serum OVA-sIgE, while the PCA result of QKL was negative with a unobvious increase in the content of serum OVA-sIgE. "

04/01/2007 - "The present study was undertaken to standardize skin testing and to develop a safe and effective premedication protocol for administration of ERIG in those with skin test positivity/hypersensitivity. "
11/01/2011 - "However, the effectiveness of premedication has not been properly demonstrated, especially in cases related to non-ionic CM. In this study, we evaluated the effectiveness of premedication at preventing of non-ionic CM immediate-type hypersensitivity reactions. "
08/01/2008 - "This study investigated the allergic reaction ratio to consider the safety and usefulness of the short-time premedication method used at our hospital. "
12/01/1994 - "In nonrandomized trials, doses studied have ranged from 135 mg/m2 to 250 mg/m2 administered over 24 hours with premedication to avoid hypersensitivity reactions (HSRs). "
02/01/1994 - "Fifty-five percent of patients demonstrated hypersensitivity reactions despite the premedication regimen employed, higher than that of the phase I studies which established the dose and schedule used in this trial. "

12/01/2005 - "Cytotoxic chemotherapy successfully induces durable complete remission in 2 patients with mosquito allergy resulting from Epstein-Barr virus-associated T-/natural killer cell lymphoproliferative disease."
12/01/2005 - "As of this writing, we have successfully treated 2 patients with mosquito allergy with chemotherapy in which EBV-infected T-/NK cells were eradicated. "
11/01/2005 - "Rapid inpatient/outpatient desensitization for chemotherapy hypersensitivity: standard protocol effective in 57 patients for 255 courses."
02/01/2013 - "We have therefore conducted this study, focusing on allergic reactions induced by each anticancer drug used in outpatient chemotherapy. "
01/01/2012 - "In this study we investigated chemotherapy-related hypersensitivity reaction in patients with gynecologic malignancy. "

08/15/1992 - "Oral administration of the allopeptide mixture to LEW responder rats daily for 5 days before immunization effected significant reduction of delayed-type hypersensitivity responses both to the allopeptide mixture and to allogeneic splenocytes. "
08/15/2008 - "In conclusion, we have shown for the first time that chronic oral administration of selective H(3) antagonists is effective in reversing neuropathic hypersensitivity in disease-related models, and that specific H(3) receptor binding sites are present in the human DRG and dorsal horn of the spinal cord. "
02/01/2001 - "In this study, we investigated the effect of cell cultured SG by oral administration in mast cell-mediated allergic reactions. "
01/01/1998 - "The aim of the present study was to evaluate whether oral administration of rDer f2 could suppress an immediate allergic reaction in mice sensitized with mite allergen. "
01/15/2015 - "Compound 40 displayed a dose dependent analgesic effect on TNBS-induced visceral hypersensitivity in rats by oral administration (ED50 0.66mg/kg at 2.5h after oral administration). "