HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The treatment of staphylococcus peritonitis in patients on continuous ambulatory peritoneal dialysis.

Abstract
The aim of this prospective, randomized, open study was to survey the frequency course and to evaluate the therapy of peritonitis induced by staphylococci in patients on continuous ambulatory peritoneal dialysis (CAPD). From June 1983 to November 1986, 20 patients (9 men, 11 women) aged from 25 to 73 were treated. During 258 months of the CAPD treatment they had 54 episodes of peritonitis. Staphylococcus saprophyticus was the most frequent offender of peritonitis, isolated from peritoneal effluent in 44% of the cases, Staphylococcus epidermidis was isolated in 7% of the cases. Staphylococcus aureus was isolated in 5% of the cases and caused a more severe form of peritonitis. The combination of gentamicin and methicillin was used in 14 cases, in 2 cases this treatment was unsuccessful. A combination of gentamicin and cloxacillin was used in 5 cases and a combination of clindamycin and mezlocillin in 12 cases of peritonitis, giving good results in all cases. The last combination seemed to be the most effective in the treatment of staphylococcus induced peritonitis.
AuthorsJ Drinovec, A Bren, A Gucek, J Lindic, A Kandus, R Ponikvar
JournalChemioterapia : international journal of the Mediterranean Society of Chemotherapy (Chemioterapia) Vol. 7 Issue 1 Pg. 46-8 (Feb 1988) ISSN: 0392-906X [Print] Italy
PMID3378276 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Anti-Bacterial Agents
  • Gentamicins
  • Clindamycin
  • Cloxacillin
  • Mezlocillin
  • Methicillin
Topics
  • Adult
  • Aged
  • Anti-Bacterial Agents (therapeutic use)
  • Clindamycin (therapeutic use)
  • Cloxacillin (therapeutic use)
  • Female
  • Gentamicins (therapeutic use)
  • Humans
  • Male
  • Methicillin (therapeutic use)
  • Mezlocillin (therapeutic use)
  • Middle Aged
  • Peritoneal Dialysis, Continuous Ambulatory
  • Peritonitis (drug therapy)
  • Prospective Studies
  • Random Allocation
  • Staphylococcal Infections (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: