Abstract | BACKGROUND:
Primary hyperparathyroidism (PHPT), which is mostly caused by a parathyroid adenoma, is fairly common in postmenopausal women but is relatively rare in pregnant women. PHPT-induced pancreatitis during pregnancy is associated with significant maternal and foetal morbidity and mortality. Diagnosis is challenging because of non-specific symptoms and changes in maternal calcium homeostasis. Information about the optimal treatment strategy for the prevention of catastrophic consequences to the mother and foetus is limited. Here, we describe a rare lethal case of severe acute necrotizing pancreatitis due to a parathyroid adenoma in a woman in her third trimester of pregnancy. CASE PRESENTATION: CONCLUSIONS: PHPT-induced acute necrotizing pancreatitis is a rare clinical entity and life-threatening condition to both the mother and the foetus during pregnancy. Early diagnosis can be challenging and is crucial. Appropriate treatment according to the patient's condition may effectively reduce maternal and foetal mortality.
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Authors | Jun Yang, Meng-Jie Dong, Feng Chen |
Journal | BMC endocrine disorders
(BMC Endocr Disord)
Vol. 19
Issue 1
Pg. 82
(Jul 29 2019)
ISSN: 1472-6823 [Electronic] England |
PMID | 31357974
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adult
- Female
- Humans
- Pancreatitis, Acute Necrotizing
(etiology, pathology, surgery)
- Parathyroid Neoplasms
(complications)
- Parathyroidectomy
(methods)
- Pregnancy
- Pregnancy Trimester, Third
- Prognosis
- Severity of Illness Index
- Young Adult
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