Abstract | BACKGROUND: OBJECTIVE: METHODS: RESULTS: - Using multivariate analysis, a model was created, which involved alkaline phosphatase and platelets and could separate patients with different patterns of fibrosis. This index showed a better performance in separating patients without fibrosis from with advanced periportal fibrosis. The biological index showed an area under the ROC curve of 1.000. Using values below the lowest or above the highest cut-off point, the presence or absence of advanced fibrosis could be predicted in all patients. CONCLUSION: - The index constructed can be used to separate patients with different patterns of periportal fibrosis, specially to predict advanced fibrosis in schistosomiasis patients.
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Authors | Ana Virgínia Matos Sá Barreto, Vinícius Martins Alecrim, Tibério Batista de Medeiros, Ana Lúcia Coutinho Domingues, Edmundo Pessoa Lopes, João Roberto Maciel Martins, Helena Bonciani Nader, George Tadeu Nunes Diniz, Silvia Maria Lucena Montenegro, Clarice Neuenschwander Lins de Morais |
Journal | Arquivos de gastroenterologia
(Arq Gastroenterol)
2017 Jan-Mar
Vol. 54
Issue 1
Pg. 51-56
ISSN: 1678-4219 [Electronic] Brazil |
PMID | 28079240
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers
- Cytokines
- Hyaluronic Acid
- gamma-Glutamyltransferase
- Transaminases
- Alkaline Phosphatase
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Topics |
- Adolescent
- Adult
- Aged
- Alkaline Phosphatase
(blood)
- Biomarkers
(blood)
- Blood Platelets
- Cytokines
(blood)
- Female
- Humans
- Hyaluronic Acid
(blood)
- Liver Cirrhosis
(blood, diagnostic imaging, parasitology)
- Male
- Middle Aged
- Predictive Value of Tests
- Schistosomiasis mansoni
(blood, complications, diagnostic imaging)
- Sensitivity and Specificity
- Severity of Illness Index
- Transaminases
(blood)
- Young Adult
- gamma-Glutamyltransferase
(blood)
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