Abstract | BACKGROUND: METHODS: Fifty male rats were divided into 2 main groups as follows: group 1 comprised 10 rats fed a standard diet (SD), and group 2 comprised 40 rats fed an HFS diet for 6 weeks and then subdivided equally into 4 groups; one of these groups served as the HFS diet and each of the other three groups received daily supplementation with either Q, CA or BB for 6 weeks. RESULTS: CONCLUSION: We showed that an HFS diet is able to promote NAFLD, and our results suggest that CA and BB are promising complementary supplements that can ameliorate the metabolic disorders associated with an HFS diet; however, Q requires further investigation.
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Authors | Sohair M M Ragab, Sary Kh Abd Elghaffar, Tarek H El-Metwally, Gamal Badr, Mohamed H Mahmoud, Hossam M Omar |
Journal | Lipids in health and disease
(Lipids Health Dis)
Vol. 14
Pg. 83
(Jul 31 2015)
ISSN: 1476-511X [Electronic] England |
PMID | 26228038
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biological Products
- Coumaric Acids
- Lipids
- PPAR gamma
- RNA, Messenger
- Berberine
- Sucrose
- Quercetin
|
Topics |
- Animals
- Berberine
(pharmacology, therapeutic use)
- Biological Products
(pharmacology, therapeutic use)
- Coumaric Acids
(pharmacology, therapeutic use)
- Diet, High-Fat
(adverse effects)
- Feeding Behavior
- Lipids
(blood)
- Liver
(drug effects, metabolism, pathology, ultrastructure)
- Male
- Non-alcoholic Fatty Liver Disease
(blood, drug therapy, pathology)
- PPAR gamma
(genetics, metabolism)
- Quercetin
(pharmacology, therapeutic use)
- RNA, Messenger
(genetics, metabolism)
- Rats, Wistar
- Sucrose
(adverse effects)
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