Sucrose (Saccharose)

A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.

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Networked: 4194 relevant articles (160 outcomes, 440 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Stevens, Bonnie: 16 articles (05/2015 - 11/2002)
2.	Lombardo, Yolanda B: 16 articles (04/2015 - 01/2003)
3.	Brien, J F: 13 articles (01/2012 - 03/2000)
4.	Reynolds, J N: 13 articles (01/2012 - 03/2000)
5.	Chicco, Adriana: 12 articles (04/2015 - 01/2003)
6.	Harrison, Denise: 11 articles (01/2015 - 09/2005)
7.	Reynolds, James N: 11 articles (11/2014 - 04/2003)
8.	Brien, James F: 11 articles (11/2014 - 04/2003)
9.	Lautt, W Wayne: 10 articles (01/2015 - 01/2003)
10.	Taddio, Anna: 9 articles (06/2015 - 11/2003)

Related Diseases

1.	Pain (Aches) 12/01/2011 - "This study found a significant reduction in the crying subscale of the Neonatal Infant Pain subscale immediately after the introduction of an arterial needle in neonates receiving a 24% sucrose solution, compared with those who did not receive sucrose solution. " 02/01/2012 - "FT alone was significantly less effective in relieving repeated procedural pain (P < .002) than sucrose (0.2 mL/kg). " 01/01/2008 - "Infants receiving oral sucrose (n=20) showed a significant reduction in behavioral pain response 5 minutes after administration compared to those in the placebo group (n=20). " 03/01/1996 - "There was a significant reduction in the duration of first cry, the percentage of time spent crying in the 5 minutes after heel prick, and the pain score in the sucrose treated group. " 08/01/2010 - "The purpose of this study was to test the efficacy of treating the pain among newborn infants associated with a medical procedure with sucrose with regard to overall physiological and behavioral stability. "
2.	Body Weight (Weight, Body) 05/01/2005 - "Body weights were significantly greater in the sucrose group than in the control group in 18-week-old rats (P<0.05), and the difference between the two groups reached 163 g by the end of the study (P<0.01). " 09/05/2008 - "Here we observed that rats receiving a variety of chronic unpredictable mild stressors for 3 weeks showed a variety of depression-like behavioral changes, including a significant reduction in body weight, sucrose preference, and locomotion, rearing and grooming in open field test, and a significant increase in immobility time in forced swimming test. " 02/01/2005 - "In comparision with the normal group, rats exposed to chronic stress showed decreased body weight and a significant reduction of consumption of sucrose solution, and the duration of immobility during the forced swimming test was increased significantly. " 11/01/1998 - "Low-fat, high-sucrose diets resulted in lower body weight in both strains, as well as significantly greater body protein content in B6 mice. " 01/01/1991 - "Sucrose-ingested rats more preferred to 30% sucrose solution than control rats and body weight gain of sucrose group was significantly greater than that of controls. "
3.	Dehydration (Water Stress) 12/01/1995 - "The rapid protocol using dehydration in 0.25 mol/l and 0.5 mol/l sucrose followed by exposure to 7.0 mol/l PROH and 0.5 mol/l sucrose for 45 s was the most effective for cryopreservation of pronuclear stage mouse embryos." 01/01/2006 - "Furthermore, A seems not to be effective in predicting sucrose accumulation, although it was very effective in detecting the occurrence of plant water stress. " 05/01/2012 - "We found that this tolerance occurs irrespective of ambient dehydration conditions, and that the addition of sucrose during dry-down improved cell recovery. " 09/01/2001 - "The efficacy of sucrose combined with CaCl2 during osmotic dehydration (OD) was tested for the control of Botrytis cinerea, Colletotrichum acutatum, and Penicillium expansum growth on lightly processed apple slices. " 08/01/1976 - "An 8-day sucrose treatment following temporary water stress improved the quality of flowers and reduced the level of ABA in the petals. "
4.	Insulin Resistance 01/01/2015 - "The aim of this study was to evaluate expression stability of potential reference genes for real-time PCR gene expression studies, in rats with insulin resistance, early programmed in intrauterine environment of maternal insulin resistance and triggered by exposure to a high sucrose and fat diet in adult life. " 01/01/2014 - "In this study, we used a high fat sucrose (HFS) diet-induced pre-insulin resistance and a low dose-STZ HFS rat models to study the effect and mechanism of Lactobacillus casei Zhang in protecting against T2DM onset. " 03/14/2013 - "In this study, two experimental diets, a high-fat diet (for 4 weeks) and 35 % sucrose solution (for 9 and 16 weeks), were used to induce insulin resistance in rats. " 01/01/2012 - "The aim of the present study was to investigate this effect on the sucrose-induced insulin resistance male rat model. " 07/01/2009 - "The present study investigates the benefits of dietary intake of soya protein upon dyslipidaemia and insulin resistance in rats chronically (8 months) fed a sucrose-rich (63 %) diet (SRD). "
5.	Hemophilia A (Haemophilia) 01/01/2008 - "Sucrose-formulated octocog alfa is effective and well tolerated as a FVIII replacement therapy in patients with haemophilia A, including those with severe disease undergoing major surgery. " 01/01/2008 - "Sucrose-formulated octocog alfa: a review of its use in patients with haemophilia A." 07/01/2000 - "Pharmacokinetics, prophylactic effects, and safety of a new recombinant FVIII formulated with sucrose (BAY 14-2222) in Japanese patients with hemophilia A." 01/01/2008 - "Available data indicate that sucrose-formulated octocog alfa is an appropriate alternative to other recombinant FVIII products for the treatment and prophylaxis of bleeding episodes in adults and children with haemophilia A." 01/01/2008 - "Sucrose-formulated octocog alfa is approved in the EU and US for the treatment of bleeding in patients with haemophilia A (congenital FVIII deficiency). "

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Factor VIII (Coagulation Factor VIII)
3.	Fructose
4.	Sodium
5.	Lactose
6.	Lidocaine (Xylocaine)
7.	Prilocaine (Citanest)
8.	Formaldehyde (Formol)
9.	Insulin (Novolin)
10.	DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1.	Pacifiers
2.	Analgesia
3.	Oral Administration
4.	Fluid Therapy (Oral Rehydration Therapy)
5.	Massage (Reflexology)