Abstract | BACKGROUND: METHODS: From the birth cohort of a MOthers and Children's Environmental Health (MOCEH) study, 257 infants, whose parents agreed with the environmental measurement, were enrolled. Total VOCs were measured in infant's bedrooms at the age of 6 month. A total of 105 parents answered a questionnaire at 36 month. Concentrations of TVOCs were divided into two groups by third quartile (75th). Associations between the high VOCs exposure group and development of atopic dermatitis at the age of 36 months were estimated by multivariate logistic regression. RESULTS: The average concentration of TVOCs was 174.7 ± 115.1 ㎍/m(3) . We defined the high TVOCs exposure group by those with more than 75 percentile of the distribution (242.1 ㎍/m(3) ). An increased risk of atopic dermatitis was observed in the high TVOCs exposure group, after adjustment for parents history of allergy, household income, breast-feeding longer than 6 month (OR = 3.116, 95% Cl 1.041-9.323). Risk of atopic dermatitis was increased when the family bought new furniture within 1 yr. CONCLUSION: Our results showed that exposure to high concentration of VOCs during infancy, an indoor pollutant, increased the risk of atopic dermatitis at 36 months.
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Authors | Jung Hyun Kwon, Eunjeong Kim, Moon-Hee Chang, Eun Ae Park, Yun-Chul Hong, Mina Ha, Hyesook Park, Yangho Kim, Choonghee Park, Eun-Hee Ha |
Journal | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
(Pediatr Allergy Immunol)
Vol. 26
Issue 4
Pg. 352-8
(Jun 2015)
ISSN: 1399-3038 [Electronic] England |
PMID | 25868723
(Publication Type: Journal Article)
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Copyright | © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Volatile Organic Compounds
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Topics |
- Air Pollution, Indoor
(adverse effects, statistics & numerical data)
- Child, Preschool
- Cohort Studies
- Dermatitis, Atopic
(epidemiology)
- Environmental Exposure
(adverse effects, statistics & numerical data)
- Female
- Follow-Up Studies
- Humans
- Infant
- Korea
(epidemiology)
- Male
- Prevalence
- Surveys and Questionnaires
- Volatile Organic Compounds
(adverse effects)
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