Abstract | PURPOSE: METHODS: This is a 5-year community-based prospective study. The demographic information, systemic examination results and ophthalmological test results of each participant were collected. The study outcomes were DR incidence, defined as the onset of DR in at least one eye, and DR regression, defined as full regression from existing DR to no retinopathy without invasive treatments. The associations between each potential risk factor and the outcomes were studied. RESULTS: In total, 778 participants were enrolled. There were 322 patients without DR at baseline, of which 151 participants developed DR during follow-up (DR incidence rate = 46.89%). Baseline hyperglycemia and high blood pressure were two independent risk factors associated with DR incidence. Among the 456 participants with existing DR at entry, 110 fully recovered after 5 years (DR regression rate = 24.12%). Low baseline glucose and low serum triglyceride were two independent factors associated with DR regression. CONCLUSIONS:
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Authors | Peiyao Jin, Jinjuan Peng, Haidong Zou, Weiwei Wang, Jiong Fu, Binjie Shen, Xuelin Bai, Xun Xu, Xi Zhang |
Journal | PloS one
(PLoS One)
Vol. 9
Issue 11
Pg. e113359
( 2014)
ISSN: 1932-6203 [Electronic] United States |
PMID | 25402474
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Glycated Hemoglobin A
- Insulin
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Topics |
- Age of Onset
- Aged
- Aged, 80 and over
- China
(epidemiology)
- Diabetes Mellitus, Type 2
(complications)
- Diabetic Retinopathy
(epidemiology, etiology)
- Female
- Follow-Up Studies
- Glycated Hemoglobin
(analysis)
- Humans
- Hyperglycemia
(physiopathology)
- Hypertension
(physiopathology)
- Incidence
- Insulin
(metabolism)
- Male
- Middle Aged
- Prognosis
- Prospective Studies
- Risk Factors
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