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Diabetic Retinopathy (Retinopathy, Diabetic)

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
Also Known As:
Retinopathy, Diabetic; Diabetic Retinopathies; Retinopathies, Diabetic
Networked: 14818 relevant articles (721 outcomes, 3045 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Macular Edema
2. Macular Degeneration (Age-Related Maculopathy)
3. Retinal Vein Occlusion
4. Type 2 Diabetes Mellitus (MODY)
5. Cataract (Cataracts)

Experts

1. Kowluru, Renu A: 91 articles (02/2022 - 09/2002)
2. Klein, Ronald: 69 articles (06/2020 - 01/2002)
3. Simó, Rafael: 65 articles (03/2022 - 09/2002)
4. Wong, Tien Yin: 60 articles (02/2022 - 02/2002)
5. Raman, Rajiv: 59 articles (11/2022 - 10/2005)
6. Sivaprasad, Sobha: 58 articles (11/2022 - 08/2008)
7. Aiello, Lloyd Paul: 57 articles (01/2022 - 01/2002)
8. Hernández, Cristina: 54 articles (03/2022 - 09/2002)
9. Sun, Jennifer K: 53 articles (01/2022 - 05/2008)
10. Mohammad, Ghulam: 51 articles (02/2022 - 03/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Diabetic Retinopathy:
1. Retinaldehyde (Retinal)IBA
2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
3. Bevacizumab (Avastin)FDA Link
4. Ranibizumab (Lucentis)FDA Link
5. afliberceptIBA
6. ArgonIBA
7. Insulin (Novolin)FDA Link
8. Fenofibrate (CiL)FDA LinkGeneric
9. Streptozocin (Streptozotocin)FDA Link
10. Pharmaceutical PreparationsIBA

Therapies and Procedures

1. Light Coagulation
2. Lasers (Laser)
3. Therapeutics
4. Vitrectomy
5. Intravitreal Injections
01/01/2016 - "Intravitreal injections improved best-corrected visual acuity (BCVA) significantly from 22.23±16.33 Early Treatment of Diabetic Retinopathy Study (ETDRS) letters to 36.23±15.19 letters (P<0.001), and mean central subfield thickness significantly reduced from 387±115 µm to 321±115 µm (P=0.01). "
08/01/2021 - "Since human CD34+ bone marrow stem cells (BMSCs) have the potential to promote revascularization of ischemic tissue, this study tests the hypothesis that intravitreal injection of human CD34+ BMSCs can have protective effects on all layers of the retinal vasculature in eyes with diabetic retinopathy. "
01/01/2020 - "This study used a murine model to test the hypothesis that intravitreal injection of human CD34 + stem cells harvested from bone marrow (BMSCs) can have protective effects in eyes with diabetic retinopathy. "
12/23/2021 - "For each eye using Alleye, we matched 2-4 controls not using home-monitoring based on age, gender, number of previous intravitreal injections (IVI), best corrected visual acuity (BCVA) (Early Treatment Diabetic Retinopathy Study letters), central macular thickness (CRT) and time point of enrolment, using the Mahalanobis distance matching algorithm. "
01/01/2018 - "Intravitreal injections per study eye during the first 12 months; corrected visual acuity, change in corrected visual acuity from baseline, proportions of eyes with ≥10 or ≥15 approximate Early Treatment Diabetic Retinopathy Study letter gain/loss at 12 months; number of ophthalmologist visits. "