Abstract | BACKGROUND & OBJECTIVES: HIV/ AIDS patients may have renal involvement also, however, Indian data are sparse. The present study was done to find the spectrum of renal diseases in HIV/ AIDS patients in north India. METHODS: In this prospective pilot study, HIV positive patients aged >18 yr were screened for renal involvement [serum creatinine >1.5 mg% and/or significant proteinuria (>500 mg /day)]. Patients who were positive on screening were followed up prospectively and underwent kidney biopsy if indicated. RESULTS: INTERPRETATION & CONCLUSIONS: Renal involvement was found to be common in HIV positive patients (17.3%). A low occurrence of renal involvement found in patients already on ART suggests some renoprotective effect of ART. Our preliminary results showed that collapsing FSGS was not rare in Indian HIV positive population, but classical HIV associated nephropathy was not seen. Longitudinal studies with robust study design and large sample size need to be done to confirm the findings.
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Authors | Vijay Gupta, Sanjay Gupta, Sanjeev Sinha, S K Sharma, A K Dinda, S K Agarwal, S C Tiwari, Meera Ekka |
Journal | The Indian journal of medical research
(Indian J Med Res)
Vol. 137
Issue 5
Pg. 950-6
(May 2013)
ISSN: 0971-5916 [Print] India |
PMID | 23760382
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- AIDS-Associated Nephropathy
(blood, etiology, pathology)
- Adult
- Creatinine
(blood)
- Female
- HIV Infections
(complications, physiopathology)
- HIV Seropositivity
- Humans
- India
- Kidney
(pathology)
- Male
- Pilot Projects
- Prospective Studies
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