Abstract | BACKGROUND: METHODS: In this study, 101 patients (American Society of Anesthesiology physical status I and II) who underwent abdominal hysterectomy were divided into 3 groups according to history of exposure to cigarette smoke as per medical records which was retrospectively confirmed by measurement of serum cotinine: smokers (n = 28), nonsmokers (n = 31), and secondhand smokers (n = 32). All patients received propofol- remifentanil total intravenous anesthesia and used fentanyl patient controlled analgesia for postoperative pain. The fentanyl consumption visual analogue scale- pain intensity (VAS-PI) score and side effects were recorded in the postanesthesia care unit (PACU) and at 2, 4, 6, and 24 h after surgery. RESULTS:
Fentanyl consumption at all the evaluation time points was significantly higher in secondhand smokers than in nonsmokers (P < 0.05). However, fentanyl consumption in secondhand smokers was lower than that in smokers in the PACU and at 24 h (P < 0.05). VAS-PI scores during movement and at rest in the PACU and at 4, 6, and 24 h after surgery were higher in secondhand smokers than in nonsmokers (P < 0.05). There were no statistically significant differences between the groups with regard to side effects such as nausea, vomiting, and dizziness (P > 0.05). CONCLUSION:
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Authors | Mustafa Said Aydogan, Erdogan Ozturk, Mehmet Ali Erdogan, Aytac Yucel, Mahmut Durmus, Mehmet Ozcan Ersoy, Cemil Colak |
Journal | Journal of anesthesia
(J Anesth)
Vol. 27
Issue 4
Pg. 569-74
(Aug 2013)
ISSN: 1438-8359 [Electronic] Japan |
PMID | 23397133
(Publication Type: Journal Article, Observational Study)
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Chemical References |
- Anesthetics, Intravenous
- Piperidines
- Tobacco Smoke Pollution
- Remifentanil
- Fentanyl
- Propofol
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Topics |
- Adult
- Aged
- Anesthetics, Intravenous
(administration & dosage)
- Female
- Fentanyl
(administration & dosage)
- Humans
- Middle Aged
- Pain Measurement
(methods)
- Pain, Postoperative
(chemically induced, drug therapy)
- Piperidines
(administration & dosage)
- Propofol
(administration & dosage)
- Prospective Studies
- Remifentanil
- Retrospective Studies
- Tobacco Smoke Pollution
(adverse effects)
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