Abstract | BACKGROUND: Alcohol ketoacidosis is a frequently missed diagnosis, but is well described in the literature. We present a case of ketoacidosis, likely alcohol ketoacidosis, in a 40 y-old chronic alcoholic patient. The detection of trace serum isopropanol prompted a discussion of alcohol ketoacidosis versus toxic isopropanol ingestion or a combination of both, including comparisons with citations in current literature. METHODS: The automated instruments used to analyze the patient's urine, blood, and serum samples are described. RESULTS: The initial impression was severe metabolic acidosis with an increased anion gap and normal serum glucose and whole blood lactate. Testing for potential toxic ingestions detected only increased serum acetone and trace serum isopropanol. A urinalysis positive for ketones and an increased serum β-hydroxybutyrate concentration clenched the diagnosis of ketoacidosis. CONCLUSION:
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Authors | Jessica B Dwyer, Kenichi Tamama |
Journal | Clinica chimica acta; international journal of clinical chemistry
(Clin Chim Acta)
Vol. 415
Pg. 245-9
(Jan 16 2013)
ISSN: 1873-3492 [Electronic] Netherlands |
PMID | 23159845
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2012 Elsevier B.V. All rights reserved. |
Chemical References |
- Blood Glucose
- Acetone
- Lactic Acid
- 2-Propanol
- 3-Hydroxybutyric Acid
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Topics |
- 2-Propanol
(blood, urine)
- 3-Hydroxybutyric Acid
(urine)
- Acetone
(blood, urine)
- Adult
- Alcoholism
(blood, complications, diagnosis, urine)
- Blood Glucose
(analysis)
- Chronic Disease
- Humans
- Ketosis
(blood, complications, diagnosis, urine)
- Lactic Acid
(blood)
- Male
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