Ketones

08/01/1988 - "Thus, the inability of exercise to enhance the metabolic clearance of ketones at high physiological plasma ketone levels is a general phenomenon that applies to both endogenous and exogenous ketosis."
10/01/2009 - "It is concluded that supplementing PG as a dry product via incorporating into the TMR is as effective as when used as a top dress, based on the efficacies of both delivery methods to numerically reduce urine ketones concentrations and, therefore, the incidence for subclinical ketosis during the first 21 days of lactation. "
01/01/2014 - "She exhibited ketoacidosis and a remarkably strong ion gap, except for ketones. "
01/01/2014 - "The patients were divided into ketosis-resistant diabetes (KRD), DKWA and DKA groups on the basis of urinary ketones, blood pH and bicarbonate levels. "
12/01/2013 - "The final multivariable regression model for urine osmolality included USG and the presence of ketones; ketonuria had a small negative association with urine osmolality. "

06/15/2015 - "Synthesis and antiproliferative activity of α-branched α,β-unsaturated ketones in human hematological and solid cancer cell lines."
04/01/2011 - "A series of novel γ-carboline ketones were designed, synthesized and evaluated for their cytotoxic activity in vitro against six human cancer cell lines (A549, SGC, HCT116, MCF-7, K562 and K562R). "
01/01/2008 - "The title compound, C(13)H(14)O(4), belongs to the class of α,β-unsaturated ketones, which have potential bactericidal, fungicidal, anti-tumor and anti-inflammatory properties. "
11/01/2006 - "Cytotoxic activity of selected trifluoromethyl ketones against oral tumor cells."
03/01/2004 - "Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells."

04/01/2005 - "However, serum ketones do not reflect weight loss."
08/01/2008 - "The most important observations were a permanent urinary excretion of ketones, up to a 3-fold increase in free fatty acid plasma levels, a mean weight loss of 0.26 kg/d, and an initially secondary hyperaldosteronism. "
04/01/2005 - "Urinary ketones reflect serum ketone concentration but do not relate to weight loss in overweight premenopausal women following a low-carbohydrate/high-protein diet."
12/01/2004 - "Rats presenting a level of hyperglycemia similar to diabetic animals, but not showing the marked weight loss or appearance of urinary ketones typical of the later group present no decline in state 3 mitochondrial oxygen consumption, the values being indistinguishable from those of mitochondria from control animals. "
07/01/2007 - "Signs that food restrictions have gone too far include weight loss or lack of weight gain, undereating to avoid insulin therapy, positive urinary ketones, and intentional restriction of healthy foods. "

11/01/2005 - "This attribute has been exploited recently to shift the adult brain toward ketone metabolism after traumatic brain injury (TBI), resulting in increased cerebral uptake and oxidation of exogenously administered ketones and improved cerebral energy. "
01/01/2011 - "Studies suggest that during times of acute brain injury, cerebral uptake of ketones increases significantly. "
01/01/2011 - "Clinical review: ketones and brain injury."
01/01/2006 - "Based on recent work demonstrating age-dependent ketogenic neuroprotection after traumatic brain injury (TBI), it was hypothesized that the neuroprotection among early post-weaned animals was related to induced cerebral transport of ketones after injury. "
11/01/2005 - "Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury."

12/03/2013 - "This research (a) further substantiates previous findings of WD-induced deficits in hippocampal-dependent FN discriminations, (b) suggests that ketones may be protective against diet-induced cognitive impairment, and (c) provides evidence that diet-induced cognitive impairment precedes weight gain and obesity."
12/03/2013 - "For rats fed the KETO diet, FN performance and BBB integrity were more closely associated with level of circulating ketone bodies than with obesity phenotype (DR or DIO), with higher levels of ketones appearing to provide a protective effect. "
04/01/2009 - "The aim of this study was to evaluate whether BC decreases blood glucose, as well as cholesterol, triglyceride (TG) and ketones levels, which can be elevated by obesity and stress in Type 2 diabetic patients. "
04/01/2007 - "In addition to obesity, family history of T2DM, and absence of GAD-65 antibodies, children with new-onset T2DM may be distinguished from those with T1DM by a combination of biochemical parameters (C-peptide, IGFBP-1, CO(2), and urine ketones)."
03/01/2001 - "We examined relationships between ventilation, plasma insulin, leptin, ketones, and blood glucose levels in two mouse models of IDDM: (1) streptozotocin-induced diabetes in C57BL/6J mice on a regular diet or with induced obesity from a high fat diet; and (2) spontaneous diabetes mellitus in NOD-Ltj mice. "