Abstract | OBJECTIVE: DESIGN: Cross-sectional cohort study. METHODS: Cardiometabolic variables, body fat distribution, cognitive function and mood were studied in the 1066 participants of the Edinburgh Type 2 Diabetes Study, of whom 162 (15%) were taking systemic, topical or inhaled glucocorticoids. RESULTS: CONCLUSIONS:
Glucocorticoids are prescribed commonly for people with type 2 diabetes despite being associated with adverse indices of glycaemic control, cardiovascular risk factors, mood and cognitive function.
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Authors | Rebecca M Reynolds, Javier Labad, Alison V Sears, Rachel M Williamson, Mark W J Strachan, Ian J Deary, Gordon D O Lowe, Jackie F Price, Brian R Walker, Edinburgh Type 2 Diabetes study investigators |
Journal | European journal of endocrinology
(Eur J Endocrinol)
Vol. 166
Issue 5
Pg. 861-8
(May 2012)
ISSN: 1479-683X [Electronic] England |
PMID | 22408122
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Aged
- Cohort Studies
- Cross-Sectional Studies
- Diabetes Complications
(blood, epidemiology)
- Diabetes Mellitus, Type 2
(blood, drug therapy, epidemiology)
- Female
- Glucocorticoids
(adverse effects, therapeutic use)
- Glucose Metabolism Disorders
(blood, chemically induced, epidemiology)
- Humans
- Male
- Memory Disorders
(blood, chemically induced, epidemiology)
- Middle Aged
- Mood Disorders
(blood, chemically induced, epidemiology)
- Prospective Studies
- Scotland
(epidemiology)
- Treatment Outcome
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