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Ocular sarcoidosis in a Korean population.

Abstract
The aim of current study was to evaluate the incidence and characteristics of ocular sarcoidosis in a Korean population. We conducted a retrospective study of 104 consecutive patients with biopsy-proven sarcoidosis seen at Asan Medical Center in Seoul, Korea, from 1993 to 2007. Medical records, photographs, and fluorescein angiograms were reviewed. Of 104 patients, 22 (21%) had intraocular involvement with female predominance (86%, M:F=3:19). Of the 39 eyes with ocular involvement, 16 (41%) eyes had isolated anterior uveitis, 12 (31%) eyes had intermediate uveitis, 6 eyes (15%) had panuveitis with retinal vasculitis, and 5 (13%) eyes had panuveitis with punched multifocal choroiditis. Mean duration of ophthalmologic follow-up was 62 months. All ocular inflammation was well managed with topical steroid and/or systemic steroid with relatively good final visual outcomes. Ocular complications such as cataract (12 eyes, 30%), glaucoma (6 eyes, 15%), vitreous opacity (1 eye, 3%), cystoid macular edema (3 eyes, 7%), neovascularization (2 eye, 5%), and epiretinal membrane (4 eye, 10%) were related to ocular sarcoidosis. In Korea, where sarcoidosis is very rare, our study indicates relatively low ocular and predominantly non posterior segment involvement with relatively good visual prognosis.
AuthorsSun Young Lee, Hee Gyung Lee, Dong Soon Kim, June-Gone Kim, Hyewon Chung, Young Hee Yoon
JournalJournal of Korean medical science (J Korean Med Sci) Vol. 24 Issue 3 Pg. 413-9 (Jun 2009) ISSN: 1598-6357 [Electronic] Korea (South)
PMID19543502 (Publication Type: Journal Article)
Chemical References
  • Steroids
Topics
  • Adult
  • Age Factors
  • Asian People
  • Choroiditis (diagnosis)
  • Eye Diseases (diagnosis, epidemiology, therapy)
  • Female
  • Fluorescein Angiography
  • Humans
  • Male
  • Middle Aged
  • Retinal Vasculitis (diagnosis)
  • Retrospective Studies
  • Sarcoidosis (diagnosis, epidemiology, therapy)
  • Steroids (therapeutic use)
  • Uveitis, Anterior (diagnosis)
  • Uveitis, Intermediate (diagnosis)

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