Hydrolysis of nucleoside triphosphate in plasma membranes of the hepatocytes of normal, regenerating and foetal livers and in cancer cells of hepatomas.

Abstract

Electron histochemical studies show that changes in the nucleoside triphosphatase activity in plasma membranes of cancer cells can proceed in different directions. Some cells show a high activity of magnesium-dependent NTPase over the whole membrane surface (perimeter), while others have a low enzymic activity which is present only in certain regions of the membranes, the remaining cells possessing no enzyme activity at all. These changes are not strictly characteristic of cancer cells alone.

• Authors: N A Filippova
• Journal: Folia histochemica et cytochemica (Folia Histochem Cytochem (Krakow)) Vol. 14 Issue 4 Pg. 233-6 ( 1976) ISSN: 0015-5586 [Print] Poland
• PMID: 192642 (Publication Type: Journal Article)

Chemical References

• Nucleotides
• Phosphoric Monoester Hydrolases

Topics

• Animals
• Carcinoma, Hepatocellular (enzymology)
• Cell Membrane (enzymology, ultrastructure)
• Fetus (enzymology)
• Histocytochemistry
• Humans
• Hydrolysis
• Liver (cytology, enzymology)
• Liver Neoplasms (enzymology)
• Liver Regeneration
• Mice
• Nucleotides (metabolism)
• Phosphoric Monoester Hydrolases (metabolism)