Magnesium

A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.

Networked: 8046 relevant articles (418 outcomes, 1362 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Maier, Jeanette A M: 19 articles (01/2015 - 02/2003)
2.	Yang, Chun-Yuh: 16 articles (01/2013 - 12/2002)
3.	Touyz, Rhian M: 15 articles (12/2015 - 11/2002)
4.	Crowther, Caroline A: 14 articles (06/2015 - 08/2007)
5.	Spasov, A A: 14 articles (04/2013 - 02/2001)
6.	Konrad, Martin: 13 articles (04/2015 - 02/2002)
7.	Iezhitsa, I N: 13 articles (04/2013 - 09/2003)
8.	Mazur, Andrzej: 13 articles (03/2010 - 01/2002)
9.	Duley, Lelia: 12 articles (01/2013 - 06/2002)
10.	Saver, Jeffrey L: 11 articles (01/2016 - 05/2004)

Related Diseases

1.	Pain (Aches) 01/01/2015 - "Intra-articular magnesium resulted in a significant reduction in pain scores in group M compared with group C 1 h, 2 h, 6 h, 8 h and 12 h after the end of surgery, respectively, at rest and with passive motion. " 03/01/2013 - "In the magnesium group, the patients' numerical rating scales revealed a significant reduction in pain intensity. " 05/01/2010 - "These data imply that intravenous magnesium therapy, besides a supposed beneficial effect on outcome, also provides pain relief for SAH patients, for whom it might also improve functional outcome." 07/01/2009 - "Intravenous magnesium significantly improved pain, impairment and quality of life and was well tolerated. " 09/01/2006 - "Intra-articular magnesium administration resulted in a significant reduction in pain scores in Group M compared with Group C 1, 2, 6 and 8 h after the end of surgery [1.7 (0.59), 2.2 (0.69), 2.8 (1.01) and 3.5 (1.10) in Group M; 8.0 (1.25), 5.9 (1.12), 4.4 (0.67) and 4.5 (1.13) in Group C, respectively]. "
2.	Eclampsia 10/01/2010 - "Simulation training is superior to traditional lecture alone for teaching crucial skills for the optimal management of both eclampsia and magnesium toxicity, 2 life-threatening obstetric emergencies." 01/01/2010 - "Six (11,444 women) compared magnesium sulphate with placebo or no anticonvulsant: magnesium sulphate more than a halved the risk of eclampsia (risk ratio (RR) 0.41, 95% confidence interval (CI) 0.29 to 0.58; number needed to treat for an additional beneficial outcome (NNTB) 100, 95% CI 50 to 100), with a non-significant reduction in maternal death (RR 0.54, 95% CI 0.26 to 1.10) but no clear difference in serious maternal morbidity (RR 1.08, 95% CI 0.89 to 1.32). " 09/01/2013 - "The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in controlling fits in eclampsia Between January and June 2011, 98 eclamptic mothers presenting at the labour ward of the University of Maiduguri Teaching Hospital were randomised to receive either the standard Pritchard regimen of magnesium sulphate or a shortened postpartum course in which only two doses of intramuscular magnesium sulphate is given four hours apart. " 09/01/2013 - "The shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in the management of eclampsia." 05/01/2011 - "In a randomised control study, we evaluated the efficacy of intravenous low-dose magnesium sulphate for the management of eclampsia. "
3.	Asthma (Bronchial Asthma) 12/01/2009 - "We hypothesized that smooth muscle cell relaxation by magnesium might also be beneficial in chronic severe asthma with persistent airflow limitation. " 09/01/2009 - "Magnesium seems to be beneficial in the treatment of moderate to severe asthma in children. " 09/01/1999 - "At 30 minutes, compared with the placebo group, the magnesium sulphate receiving group had lower clinical asthma scores (4.0+/-0.5 vs. 5.5+/-0.5, p = 0.0002) and a significantly greater percentage of improvement from baseline in PEFR (43.0+/-6.3% vs. 14.6+/-3.7%, p = 0.0002). " 12/01/1996 - "Children treated with intravenous magnesium infusions for moderate to severe asthma had significantly greater improvement in short-term pulmonary function without any significant alteration in blood pressure, suggesting a role for this agent as an adjunct in the treatment of such patients." 11/01/2014 - "Several authors reported that IV magnesium was effective in the treatment of moderate to acute asthma in children but evidence for nebulised magnesium was insufficient. "
4.	Myocardial Infarction 11/24/1995 - "Intravenous magnesium therapy in acute myocardial infarction (MI) has been shown to be beneficial in many studies. " 12/01/1988 - "The observed hemodynamic effects of the magnesium infusions may be beneficial in the setting of an acute myocardial infarction by reducing left ventricular afterload, which, together with the antiarrhythmic effect of magnesium may contribute to the positive effect of magnesium infusions on mortality in patients with acute myocardial infarction." 09/01/1992 - "Intravenous magnesium is a safe and effective method of reducing the frequency of arrhythmias and mortality in acute myocardial infarction." 01/01/2008 - "We searched the literature for all randomized clinical trials (RCT) and review articles on the efficacy of intravenous magnesium in the early post-myocardial infarction period. " 03/01/2003 - "Nevertheless, because of conflicting results of prior trials doubts on the efficacy of intravenous magnesium in myocardial infarction still remain. "
5.	Seizures (Seizure) 06/01/2007 - "Magnesium sulphate is the most effective agent for seizure prophylaxis. " 01/01/2003 - "There are unequivocal evidences that Magnesium sulphate is superior to other agents in reducing recurrent eclamptic seizures. " 09/01/2000 - "Audit can ensure the safe and effective introduction of seizure prophylaxis with magnesium sulphate in obstetric practice." 08/01/1996 - "Results of this study show a trend that is in agreement with recent randomized controlled trials which demonstrate a reduced incidence of seizures and maternal and fetal complications with the use of magnesium sulphate. " 07/01/1988 - "When magnesium is eliminated from the medium bathing the hippocampal slice, spontaneously occurring electrical events which closely resemble electrographic seizures can be recorded extracellularly from area CA3. "

Related Drugs and Biologics

1.	Calcium
2.	Potassium
3.	Phosphorus
4.	N-Methylaspartate (NMDA)
5.	Sodium
6.	Phenytoin (Dilantin)
7.	Riboflavin (Vitamin B2)
8.	Zinc
9.	Magnesium Sulfate (Sulfate, Magnesium)
10.	Insulin (Novolin)

Related Therapies and Procedures

1.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
2.	Stents
3.	Renal Dialysis (Hemodialysis)
4.	Resuscitation
5.	Tonsillectomy