Abstract | OBJECTIVE: METHODS: RESULTS: The biomarker proteins such as fibrinogen gamma chain, albumin and apolipoprotein AI (precursor) in discrimination of the patients with phlegm syndrome from phlegm accumulating with stagnation syndrome were correlated with the deficiency of kidney-qi, heart-qi and spleen-qi. Among the four biomarker proteins in discrimination of the patients with phlegm syndrome from blood stagnation syndrome, albumin, adrenomedullin binding protein (precursor) and haptoglobin (precursor) were correlated with the deficiency of kidney-qi and heart-qi, but complement component C4 was independent of the deficient Zang-Fu organs. The biomarker albumin was associated with the deficiency of kidney-qi, heart-qi and spleen-qi, and adrenomedullin binding protein (precursor) was correlated with the deficiency of spleen-qi in discrimination of the patients with blood stagnation syndrome from phlegm accumulating with stagnation syndrome. As the potential biomarker proteins in discrimination of the patients with non-phlegm and non-stagnation syndrome from phlegm accumulating with stagnation syndrome, the fibrinogen beta chain was related with the deficiency of kidney-qi, and apolipoprotein AI (precursor) was correlated with both the deficiency of kidney-qi and heart-qi. CONCLUSION:
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Authors | Jian-nan Song, Jun-lian Liu, Xiang-zhong Fang, Yuan-hui Hu, Yan Lei, Xiao-hong Niu, Gang Wu, Bao-sheng Chen, Ya-luan Ma, Bing Chen, Hong Jin |
Journal | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
(Zhong Xi Yi Jie He Xue Bao)
Vol. 6
Issue 12
Pg. 1233-7
(Dec 2008)
ISSN: 1672-1977 [Print] China |
PMID | 19063835
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Atherosclerosis
(blood, diagnosis, physiopathology)
- Blood Proteins
(metabolism)
- Female
- Humans
- Hyperlipidemias
(blood, diagnosis, physiopathology)
- Male
- Medicine, Chinese Traditional
(methods)
- Middle Aged
- Proteome
(metabolism)
- Yang Deficiency
(blood, diagnosis, physiopathology)
- Yin Deficiency
(blood, diagnosis, physiopathology)
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