Abstract | BACKGROUND: OBJECTIVE: We analyzed the efficacy and safety of temporary placement of a covered self-expanding metal stent (CSEMS) in BBS. DESIGN: Patients with BBS received temporary placement of CSEMSs until adequate drainage was achieved; confirmed by resolution of symptoms, normalization of liver function tests, and imaging. SETTING: Tertiary-care center with long-standing experience with CSEMSs. PATIENTS: INTERVENTION: ERCP with temporary CSEMS placement. Removal of CSEMSs was performed with a snare or a rat-tooth forceps. MAIN OUTCOME MEASUREMENTS: End points were efficacy, morbidity, and clinical response. RESULTS: CSEMSs were removed from 65 patients. Resolution of the BBS was confirmed in 59 of 65 patients (90%) after a median follow-up of 12 months after removal (range 3-26 months). If patients who were lost to follow-up, developed cancer, or expired were considered failures, then an intent-to-treat global success rate of 59 of 79 (75%) was obtained. Complications associated with placement included 3 post-ERCP pancreatitis (4%), 1 postsphincterotomy bleed (1%), and 2 pain that required CSEMS removal (2%). In 11 patients (14%), the CSEMS migrated. In 1 patient, CSEMS removal was complicated by a bile leak that was successfully managed with plastic stents. LIMITATION: Pilot study from a single center. CONCLUSIONS: Temporary CSEMS placement in patients with BBS offers a potential alternative to surgery.
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Authors | Michel Kahaleh, Brian Behm, Bridger W Clarke, Andrew Brock, Vanessa M Shami, Sarah A De La Rue, Vinay Sundaram, Jeffrey Tokar, Reid B Adams, Paul Yeaton |
Journal | Gastrointestinal endoscopy
(Gastrointest Endosc)
Vol. 67
Issue 3
Pg. 446-54
(Mar 2008)
ISSN: 0016-5107 [Print] United States |
PMID | 18294506
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Coated Materials, Biocompatible
- Metals
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Cholestasis
(etiology, surgery)
- Coated Materials, Biocompatible
- Cohort Studies
- Device Removal
- Equipment Design
- Female
- Humans
- Male
- Metals
- Middle Aged
- Pilot Projects
- Prosthesis Implantation
- Stents
- Time Factors
- Treatment Outcome
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