Abstract | BACKGROUND/METHODS: RESULTS: Of the remaining 141 hemodialysis patients, 14 (9.9%) (9 males and 5 females, aged 69.1 A+/- 8.8 years with a mean duration of hemodialysis of 69 A+/- 51 months) were in a hypothyroid state, defined as a thyroid-stimulating hormone (TSH) level > 5 mU/l. Antithyroid peroxidase antibodies were positive in only 1 of the 14 patients, while antithyroglobulin antibodies were negative in all of these patients. After iodide restriction, the serum TSH level decreased in all the patients from a mean of 16.49 A+/- 22.80 to 4.44 A+/- 3.35 mU/l after 1 month, 4.25 A+/- 2.24 mU/l after 2 months and 3.97 A+/- 2.22 mU/l after 3 months. The 3 months of iodide restriction were also associated with decreases in systolic blood pressure (142 A+/- 19 to 125 A+/- 16 mmHg, p < 0.05), diastolic blood pressure (79 A+/- 13 to 72 A+/- 9 mmHg, p < 0.05) and thyroid gland volume estimated by ultrasonography (13.7 A+/- 6.3 to 11.6 A+/- 5.2 ml, p < 0.05). CONCLUSION:
|
Authors | T Sanai, T Inoue, K Okamura, K Sato, K Yamamoto, T Abe, K Node, K Tsuruya, M Iida |
Journal | Clinical nephrology
(Clin Nephrol)
Vol. 69
Issue 2
Pg. 107-13
(Feb 2008)
ISSN: 0301-0430 [Print] Germany |
PMID | 18218304
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
|
Topics |
- Aged
- Aged, 80 and over
- Female
- Humans
- Hypothyroidism
(blood, complications, epidemiology)
- Japan
(epidemiology)
- Kidney Failure, Chronic
(complications, therapy)
- Male
- Middle Aged
- Prevalence
- Prognosis
- Renal Dialysis
(methods)
- Thyroid Gland
(diagnostic imaging)
- Thyrotropin
(blood)
- Ultrasonography
|