Abstract | OBJECTIVE: To investigate the clinical and pathological characteristics of primary cervical malignant melanoma, and its prognosis. METHODS: RESULTS: The average age of four patients was 45 years. Clinical symptoms presented with irregular vaginal bleeding, postcoital bleeding, or increase of vaginal discharge. Gynecologic examination showed polypus papilla cauliflower-shaped or nodulated black-brown or black-blue mass on the cervix. All the four cases were pathologically diagnosed with cervical malignant melanoma. S-100 and HMB-45 were positive in all patients. Two patients died at 6 and 41 months postoperation, respectively. The other two patients survived for 3.5 and 7 years postoperation, respectively. CONCLUSIONS:
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Authors | Shui-qing Ma, Chun-mei Bai, Sen Zhong, Xiao-hong Yu, Jing-he Lang |
Journal | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih
(Chin Med Sci J)
Vol. 20
Issue 4
Pg. 257-60
(Dec 2005)
ISSN: 1001-9294 [Print] China |
PMID | 16422255
(Publication Type: Journal Article)
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Chemical References |
- Antibodies, Monoclonal
- S100 Proteins
- Dacarbazine
- Interferon-gamma
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Topics |
- Adult
- Antibodies, Monoclonal
(metabolism)
- Chemotherapy, Adjuvant
- Dacarbazine
(therapeutic use)
- Diagnosis, Differential
- Female
- Follow-Up Studies
- Humans
- Hysterectomy
- Interferon-gamma
(therapeutic use)
- Melanoma
(immunology, pathology, therapy)
- Middle Aged
- Prognosis
- Retrospective Studies
- S100 Proteins
(metabolism)
- Uterine Cervical Neoplasms
(immunology, pathology, therapy)
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