Abstract | BACKGROUND: OBJECTIVE: METHODS: The patient was evaluated for progressive muscle weakness. Comprehensive clinical evaluation and muscle biopsy were performed for histopathologic analysis and mitochondrial DNA and respiratory chain enzyme studies. The patient began taking 150 mg/d of a CoQ(10) supplement. RESULTS: CONCLUSIONS:
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Authors | Seema R Lalani, Georgirene D Vladutiu, Katie Plunkett, Timothy E Lotze, Adekunle M Adesina, Fernando Scaglia |
Journal | Archives of neurology
(Arch Neurol)
Vol. 62
Issue 2
Pg. 317-20
(Feb 2005)
ISSN: 0003-9942 [Print] United States |
PMID | 15710863
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
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Chemical References |
- Coenzymes
- DNA, Mitochondrial
- Ubiquinone
- Lactic Acid
- Creatine Kinase
- coenzyme Q10
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Topics |
- Biopsy
(methods)
- Child
- Coenzymes
- Creatine Kinase
(urine)
- DNA, Mitochondrial
(metabolism)
- Electron Transport
(physiology)
- Humans
- Lactic Acid
(urine)
- Male
- Microscopy, Electron, Transmission
(methods)
- Mitochondria, Muscle
(enzymology, pathology, ultrastructure)
- Mitochondrial Myopathies
(diet therapy, enzymology, genetics, physiopathology)
- Muscle Weakness
(drug therapy, enzymology, genetics, physiopathology)
- Muscle, Skeletal
(enzymology, pathology, physiopathology, ultrastructure)
- Staining and Labeling
(methods)
- Ubiquinone
(administration & dosage, analogs & derivatives, deficiency)
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