Anti-inflammatory and antimicrobial activities of triterpenoids from Strobilanthes callosus nees.

Abstract

The anti-inflammatory and antimicrobial activities of the 95% ethanol extract, benzene fraction and isolated triterpenoids of Strobilanthes callosus were investigated. In the carrageenan-induced paw edema inflammation model, the taraxerol showed a high reduction of edema, but the antimicrobial effect observed was lower at the two doses employed. These results confirm the use of this plant in folk medicine as an anti-inflammatory and antimicrobial herbal drug.

• Authors: B Singh, P M Sahu, M K Sharma
• Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology (Phytomedicine) Vol. 9 Issue 4 Pg. 355-9 (May 2002) ISSN: 0944-7113 [Print] Germany
• PMID: 12120818 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Anti-Infective Agents
• Anti-Inflammatory Agents
• Plant Extracts
• Triterpenes
• Carrageenan

Topics

• Acanthaceae
• Animals
• Anti-Bacterial Agents
• Anti-Infective Agents (pharmacology)
• Anti-Inflammatory Agents (administration & dosage, therapeutic use)
• Carrageenan
• Dose-Response Relationship, Drug
• Edema (chemically induced, prevention & control)
• Fungi (drug effects)
• Gram-Negative Bacteria (drug effects)
• Gram-Positive Bacteria (drug effects)
• Humans
• Male
• Microbial Sensitivity Tests
• Phytotherapy
• Plant Extracts (administration & dosage, pharmacology, therapeutic use)
• Rats
• Rats, Wistar
• Triterpenes (administration & dosage, pharmacology, therapeutic use)