Ethanol (Ethyl Alcohol)

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.

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Networked: 16198 relevant articles (762 outcomes, 2021 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kovacs, Elizabeth J: 40 articles (11/2015 - 04/2002)
2.	Nagy, Laura E: 31 articles (01/2016 - 09/2003)
3.	Crabbe, John C: 27 articles (09/2014 - 04/2002)
4.	Luo, Jia: 24 articles (10/2015 - 05/2002)
5.	Abdel-Rahman, Abdel A: 22 articles (08/2015 - 10/2002)
6.	Gao, Bin: 21 articles (10/2015 - 05/2002)
7.	Thurman, R G: 20 articles (12/2001 - 02/2000)
8.	Choudhry, Mashkoor A: 19 articles (01/2016 - 06/2002)
9.	El-Mas, Mahmoud M: 19 articles (04/2014 - 10/2002)
10.	Vilegas, Wagner: 18 articles (11/2015 - 03/2004)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 07/14/2011 - "Ethanol injection is highly effective for hepatocellular carcinoma smaller than 2 cm." 02/01/2008 - "Percutaneous ethanol injection (PEI) is an option for hepatocellular carcinoma (HCC) treatment that is most effective for solitary lesions <or=5 cm or multiple lesions <or=3 cm. Malignant seeding along the needle tract is a rare complication of the procedure. " 03/01/2013 - "To evaluate the therapeutic efficacy and safety of percutaneous ethanol injection (PEI) alone and combined with radiofrequency ablation (RFA) for hepatocellular carcinomas (HCCs) in high risk locations. " 03/01/2013 - "Therapeutic efficacy and safety of percutaneous ethanol injection with or without combined radiofrequency ablation for hepatocellular carcinomas in high risk locations." 08/15/2002 - "Hepatocellular carcinoma in elderly patients: beneficial therapeutic efficacy using percutaneous ethanol injection therapy."
2.	Neoplasms (Cancer) 06/15/2003 - "Together, the findings provide evidence that: (a) class I ADH is the medium-chain ADH that is expressed in human breast parenchyma, specifically in the mammary epithelium; (b) human breast parenchyma can support ADH-mediated oxidation of ethanol; and (c) the expression of class I ADH is dramatically reduced or abrogated in invasive breast cancers. " 06/01/2015 - "Although percutaneous ethanol injection still plays a role, current guidelines favor radiofrequency ablation with a higher efficacy for complete tumor destruction. " 02/21/2012 - "This study opens up the possibility of improved tumor ablation therapy via a combination of percutaneous ethanol injection and high-intensity focused ultrasound." 01/01/2013 - "In DDP-resistant A549/DDP lung tumor-bearing Balb/C nude mice, intratumoral injection of 5% ethanol-DDP regressed tumors and significantly improved survivals compared with 5% ethanol, DDP alone, or control. " 01/01/2014 - "Although ethanol is more effective in certain aspects, its tumor inhibitory effects are similar to OCT‑P407 and as such, OCT‑P407 may be a suitable alternative."
3.	Ulcer 08/01/1996 - "It is highly effective against ethanol-induced ulcers. " 01/01/2014 - "africana was effective against ethanol even after the induction of ulcer, indicating that it can have protective and curative effects against gastric lesion. " 09/01/2011 - "In the model of ethanol-induced ulcers, we observed a significant reduction in all the parameters analysed; the curative ratios obtained were 49.31±0.57, 74.31±0.91 and 79.86±0.59 for the groups treated with 50 and 100mg/kg of extract of M. " 01/01/2015 - "The HEGG (50-200 mg/kg) showed a significant reduction in ulcer index in HCl/Ethanol-induced ulcer. " 11/01/2014 - "All the studied parameters indicated that the total extract of Ficus cordata at 500mg/kg possess moderate hepatoprotective effect, good protection against ethanol induced ulcer and weak nephroprotective effect. "
4.	Cysts 09/01/1994 - "The best results are obtained from the use of ethanol (30% of the volume of cyst). " 01/01/2005 - "Easy technique, low cost and very small number of complications gives to percutaneous ethanol injection the possibility to become the gold standard for the treatment of biliary cysts." 03/01/2014 - "After aspiration, there was no significant reduction in the cyst diameter (10.3mm vs 8.1mm), but after ethanol application the diameter significantly reduced (10.1mm vs 3.4mm, p<0.05). " 10/01/2011 - "The chocolate cyst cure rate was significantly higher in the ethanol retention group (96%, 66/69) than in the ethanol short-time retention group (82%, 56/68) and no case was cured in the first group (saline washing). " 07/01/2009 - "Follow-up USG was done every month for 3 months; ethanol was re-injected when there was no significant reduction in the cyst volume. "
5.	Stomach Ulcer (Gastric Ulcer) 06/28/2005 - "The findings of our study are as follows: (1) GbE pretreatment was found to provide a dose-dependent protection against the ethanol-induced gastric ulcers in rats; (2) the GbE pretreatment afforded a dose-dependent inhibition of ethanol-induced depletion of stomach wall mucus, NP-SH contents and increase in the lipid peroxidation (increase MDA) in gastric tissue; (3) gastric ulcer induced by ethanol produced an increase in JNK activity in gastric mucosa which also significantly inhibited by pretreatment with GbE; and (4) GbE alone had no inhibitory effect on gastric secretion in pylorus-ligated rats. " 03/01/2007 - "glandulosa (AG) showed a dose-dependent effect and significant reduction of gastric ulcers induced by absolute ethanol at the doses of 500 (57%) and 1000 mg/kg (85%) in relation to the control group. " 10/03/2005 - "Pharmacological experiments clearly demonstrated that the extracts of all plants given orally showed significant gastric protection against the ethanol-induced gastric ulcer model in rats. " 04/26/2005 - "The present work aimed at testing, in a rat model of ethanol-induced gastric ulceration, a local folk medicinal claim that dates are beneficial in gastric ulcers in humans. " 07/01/2012 - "A Comparison between Water and Ethanol Extracts of Rumex acetosa for Protective Effects on Gastric Ulcers in Mice."

Related Drugs and Biologics

1.	Indomethacin (Indometacin)
2.	Acetic Acid (Vinegar)
3.	Aspirin (Acetylsalicylic Acid)
4.	Acetaldehyde
5.	Ethiodized Oil (Ethiodol)
6.	Nicotine
7.	Glucose (Dextrose)
8.	Diazepam (Valium)
9.	Cocaine (Cocaine HCl)
10.	N-Methylaspartate (NMDA)

Related Therapies and Procedures

1.	Sclerotherapy
2.	Catheters
3.	Injections
4.	Ligation
5.	Self Administration (Administration, Self)