Benzene (Benzole)

Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.

Also Known As:

Networked: 1842 relevant articles (23 outcomes, 238 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Smith, Martyn T: 30 articles (01/2016 - 01/2002)
2.	Zhang, Luoping: 29 articles (01/2016 - 01/2002)
3.	Li, Guilan: 24 articles (07/2013 - 03/2002)
4.	Rothman, Nathaniel: 21 articles (11/2015 - 05/2005)
5.	Vermeulen, Roel: 20 articles (11/2015 - 05/2005)
6.	Lan, Qing: 20 articles (11/2015 - 05/2005)
7.	Yin, Songnian: 17 articles (03/2012 - 03/2002)
8.	Rappaport, Stephen M: 15 articles (01/2014 - 03/2002)
9.	Winn, Louise M: 12 articles (11/2015 - 01/2007)
10.	McHale, Cliona M: 10 articles (07/2015 - 01/2008)

Related Diseases

1.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/2002 - "Previous studies exploring whether benzene exposure induces chromosomal aberrations have yielded mostly positive results. " 01/16/1994 - "Monitoring of benzene-exposed workers for genotoxic effects of benzene: improved-working-condition-related decrease in the frequencies of chromosomal aberrations in peripheral blood lymphocytes." 04/01/2014 - "Thus, the aim of our study was to assess the frequencies of chromosomal abnormalities (CA) and sister chromatid exchanges (SCE) in workers of gas stations, with (cases, n = 19) and without (local controls, n = 6) risk of exposure to benzene and its derivatives, comparing them with the results from the general population (external controls, n = 38). " 05/01/2004 - "Benzene exposure resulted in an increase of chromosome aberrations of the peripheral lymphocytes, which was in a dose-effect relationship manner; whether benzene exposure could induce premature centromere division deserves further studies." 05/01/2004 - "To study the effects of benzene exposure on chromosome aberration of peripheral lymphocytes in workers. "
2.	Stroke (Strokes) 05/01/2002 - "It has been proposed that the novel spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059) may be useful in the treatment of ischemic stroke. " 03/01/2001 - "Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke." 03/01/2007 - "The objective of this study was to measure personal exposure to benzene as a marker of fuel exposure, and to predict exposure levels across categories of carbureted two-stroke, four-stroke and diesel engines. " 03/01/2007 - "After controlling for refueling, predicted benzene exposure levels to fishers on boats equipped with two-stroke, four-stroke and diesel engines were 58.4, 38.9 and 15.7 microg/m3, respectively. " 03/01/2007 - "Personal exposure to benzene from fuel emissions among commercial fishers: comparison of two-stroke, four-stroke and diesel engines."
3.	Neoplasms (Cancer) 02/01/2014 - "The estimated lifetime cancer risk (LCR) due to benzene in this study exceeded the value of 1 × 10(-6) recommended by USEPA, and the hazard quotient (HQ) of non-cancer risk came under an acceptable range." 01/01/2014 - "Results from this first ecologic study to incorporate quantitative measures of oil exploration and production showed no association between the extent of these activities and cancer mortality, including from cancers associated with benzene exposure." 10/01/2013 - "The present study aimed to assess the risk of cancer due to benzene in the ambient air of gas stations and traffic zones in the north of Tehran. " 07/16/2012 - "These new studies of benzene leukemogenesis and hematotoxicity are expected to provide insights into how environmental and occupational chemicals affect stem cells to cause cancer and toxicity, which impact the risk assessment, permissible level, and therapy of benzene exposure." 05/01/2011 - "Our study provides additional support to the growing body of evidence implicating low level benzene exposure and cancer risk. "
4.	Poisoning 09/01/2007 - "CIK treatment is safe and effective for hematopoietic injury caused by benzene poisoning. " 08/01/2012 - "[Clinical study of correlation between the expression of ICBP90 and hematopoietic suppression in patients with chronic benzene poisoning]." 07/01/2007 - "The aim of this study was to explore the association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning (CBP). " 06/01/2007 - "The study included 152 benzene poisoning patients, and 152 control workers occupationally exposed to benzene in South China. " 07/01/2006 - "[Study on repair capacity of DNA damage associated with chronic benzene poisoning]."
5.	Aneuploidy (Aneuploid) 07/01/2015 - "Our previous studies showed that workers exposed to benzene and FA exhibit increased levels of aneuploidy in their blood cells. " 03/01/2014 - "In populations occupationally exposed to low levels of benzene, we applied peripheral blood mononuclear cell transcriptomics and chromosome-wide aneuploidy studies in lymphocytes. " 04/01/2012 - "Occupational exposure to benzene has been associated with increased chromosomal aneuploidies in blood lymphocytes and, in separate studies, in sperm. " 04/01/2011 - "Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene." 03/01/2001 - "[Study on frequencies of aneuploidy in mouse oocyte and female pronucleus of one cell zygote induced by benzene]."

Related Drugs and Biologics

1.	benzoquinone (quinone)
2.	hydroquinone (Black and White)
3.	1,3-butadiene
4.	Biological Markers (Surrogate Marker)
5.	catechol (pyrocatechol)
6.	Formaldehyde (Formol)
7.	Carcinogens
8.	Asbestos
9.	Solvents
10.	Arsenic

Related Therapies and Procedures

1.	Immunotherapy
2.	Moxibustion
3.	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
4.	Oral Administration
5.	Hepatectomy