Total Disc Replacement

The replacement of intervertebral discs in the spinal column with artificial devices. The procedure is done in the lumbar or cervical spine to relieve severe pain resulting from INTERVERTEBRAL DISC DEGENERATION.

Also Known As:

Arthroplasty, Replacement, Disc; Arthroplasty, Replacement, Disk; Artificial Disc Replacement; Artificial Disk Replacement; Total Disc Arthroplasty; Total Disk Arthroplasty; Total Disk Replacement; Arthroplasties, Total Disc; Arthroplasties, Total Disk; Arthroplasty, Total Disc; Arthroplasty, Total Disk; Artificial Disc Replacements; Artificial Disk Replacements; Disc Arthroplasties, Total; Disc Arthroplasty, Total; Disc Replacement, Artificial; Disc Replacement, Total; Disc Replacements, Artificial; Disc Replacements, Total; Disk Arthroplasties, Total; Disk Arthroplasty, Total; Disk Replacement, Artificial; Disk Replacement, Total; Disk Replacements, Artificial; Disk Replacements, Total; Replacement, Artificial Disc; Replacement, Artificial Disk; Replacement, Total Disc; Replacement, Total Disk; Replacements, Artificial Disc; Replacements, Artificial Disk; Replacements, Total Disc; Replacements, Total Disk; Total Disc Arthroplasties; Total Disc Replacements; Total Disk Arthroplasties; Total Disk Replacements

Networked: 423 relevant articles (33 outcomes, 71 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913

Experts

1.	Yue, James J: 13 articles (12/2019 - 04/2005)
2.	Zigler, Jack E: 11 articles (02/2022 - 08/2003)
3.	Ohnmeiss, Donna D: 10 articles (04/2022 - 11/2002)
4.	Guyer, Richard D: 9 articles (04/2022 - 11/2004)
5.	Coric, Domagoj: 8 articles (04/2022 - 01/2007)
6.	Nunley, Pierce D: 8 articles (04/2022 - 04/2009)
7.	Zigler, Jack: 8 articles (10/2021 - 05/2007)
8.	Garcia, Rolando: 8 articles (08/2021 - 11/2002)
9.	Phan, Kevin: 8 articles (02/2021 - 06/2016)
10.	McAfee, Paul C: 8 articles (05/2009 - 08/2003)

Related Diseases

1.	Intervertebral Disc Degeneration 11/09/2022 - "Anterior cervical discectomy with artificial disc replacement (ADR) is an effective treatment of cervical degenerative disc disease. " 03/01/2006 - "The Prodisc lumbar total disc replacement appears to be effective and safe for the treatment of symptomatic degenerative disc disease. " 03/01/2005 - "The Prodisc lumbar total disc replacement appears to be effective and safe for the treatment of symptomatic degenerative disc disease. " 04/15/2022 - "Total disc arthroplasty (TDA) has been shown to be an effective and safe treatment for cervical degenerative disc disease at short- and midterm follow-up. " 11/04/2015 - "Total disc arthroplasty with ProDisc-C is a safe and effective surgical treatment of single-level symptomatic cervical degenerative disc disease. "
2.	Pain (Aches) 02/01/2019 - "This study presents mid-term to long-term results of extreme lateral total disc replacement artificial disc for the treatment of lumbar degenerative disease, with fast mobilization, sustained pain relief, and improved physical function. " 09/28/2023 - "Consequently, there is a call for innovation and improvement in the treatment of lumbar and cervical spine pain, which may be answered by a modern technique known as intervertebral disc arthroplasty, or total disc replacement (TDR). " 03/01/2016 - "The purpose of this study was to develop a tool to determine optimal placement and size for total disk replacements (TDRs) to improve patient outcomes of pain and function. " 10/15/2013 - "For question 1, 2 studies suggested that neurological outcomes favored artificial disc replacement compared with anterior cervical decompression and fusion, whereas functional and pain outcomes were inconsistently reported. " 08/01/2012 - "In this study, pain alleviation and quality of life (QoL) improvement after lumbar total disc arthroplasty (TDA) and anterior lumbar interbody fusion (ALIF) were anonymously compared by surgeon and implant. "
3.	Radiculopathy (Radiculopathy, Cervical) 06/01/2015 - "The Discover artificial disc replacement versus fusion in cervical radiculopathy--a randomized controlled outcome trial with 2-year follow-up." 01/01/2013 - "The purpose of this study was to evaluate the long-term results of cervical total disc replacement (TDR) and anterior cervical discectomy and fusion (ACDF) in the treatment of single-level cervical radiculopathy. " 08/01/2023 - "We aimed to elucidate the security, effectivity, and feasibility of surgery combining laminoplasty with artificial disc replacement (ADR) to treat CSM patients with radiculopathy, especially for preserving the range of motion (ROM) of the cervical spine. " 01/01/2023 - "The most effective surgical treatments for cervical radiculopathy were Mobi-c, Kineflx\|C, and artificial disc replacement compared to ACDF treatment, respectively." 04/01/2022 - "Patients may occasionally have persistent or recurrent radicular symptoms after cervical artificial disc replacement (ADR) for cervical spondylotic radiculopathy. "
4.	Spondylosis 11/04/2017 - "BACKGROUND The aim of this study was to retrospectively analyze the clinical and radiological efficacy of Bryan cervical artificial disc replacement (ADR) for "skip" multi-segment cervical spondylosis (SCS). " 07/01/2013 - "To determine the efficacy of total disc replacement (TDR) for the treatment of cervical spondylosis associated with atypical symptoms. " 09/15/2022 - "The clinical data of 56 patients with single-segment cervical spondylosis who met the selection criteria between January 2015 and December 2018 were retrospectively analyzed, and they were divided into study group (27 cases, using Prodisc-C Vivo artificial disc replacement) and control group (29 cases, using Zero-P fusion) according to different surgical methods. " 01/01/2021 - "This study suggested that two-level cervical total disc replacement or HS could become an alternative approach for therapy of two-level consecutive cervical spondylosis." 12/01/2018 - "The aim of this study was to identify the rate of return to an active duty flight status among US military pilots who had undergone anterior cervical discectomy and fusion (ACDF) or total disc replacement (TDR) for symptomatic cervical spondylosis.METHODSThe authors performed a single-center retrospective review of all active duty pilots who had undergone either ACDF or TDR at a military hospital between January 2010 and June 2017. "
5.	Low Back Pain (Lumbago) 02/01/2015 - "Lumbar total disc replacement is an effective treatment for single-level discogenic lower back pain. " 01/01/2013 - "Therefore, because we think that harm and complications may occur after some years, the spine surgery community should be prudent to adopt this technology on a large scale, despite the fact that total disc replacement seems to be effective in treating low back pain in selected patients, and in the short term is at least equivalent to fusion surgery." 09/12/2012 - "Therefore, because we believe that harm and complications may occur after years, we believe that the spine surgery community should be prudent about adopting this technology on a large scale, despite the fact that total disc replacement seems to be effective in treating low-back pain in selected patients, and in the short term is at least equivalent to fusion surgery." 02/01/2010 - "This study examines the indirect costs associated with surgery for axial low back pain using data obtained from a prospective multicenter clinical trial that compared Charité artificial disc replacement with anterior lumbar interbody fusion using iliac crest bone graft. " 01/01/2009 - "Clinical studies will be required to show whether or not there is a strong correlation of parameter combinations that cause high facet joint forces and low back pain after total disc replacement."

Related Drugs and Biologics

1.	Dichlorodiphenyldichloroethane (DDD)
2.	polyetheretherketone
3.	Polyethylene (Polythene)
4.	Capsules (Microcapsules)
5.	Solutions
6.	Metals
7.	Elements
8.	ultra-high molecular weight polyethylene (UHMWPE)
9.	Therapeutic Uses
10.	Intercellular Signaling Peptides and Proteins (Growth Factors)

Related Therapies and Procedures

1.	Diskectomy (Discectomy)
2.	Decompression
3.	Arthrodesis
4.	Therapeutics
5.	Arthroplasty