Polyethylene (Polythene)

A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.

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Networked: 2158 relevant articles (62 outcomes, 181 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kim, Young-Hoo: 16 articles (11/2015 - 05/2002)
2.	Goodman, Stuart B: 16 articles (03/2015 - 06/2006)
3.	Lachiewicz, Paul F: 13 articles (01/2016 - 05/2002)
4.	Kyomoto, Masayuki: 13 articles (09/2015 - 10/2006)
5.	Callaghan, John J: 13 articles (08/2014 - 08/2002)
6.	Engh, Charles A: 13 articles (06/2011 - 01/2002)
7.	Moro, Toru: 12 articles (09/2015 - 07/2007)
8.	Engh, Gerard A: 12 articles (01/2012 - 06/2002)
9.	Kurtz, Steven M: 11 articles (10/2015 - 01/2007)
10.	Takatori, Yoshio: 11 articles (09/2015 - 07/2007)

Related Diseases

1.	Osteolysis 04/01/2013 - "Despite the widespread implementation of highly cross-linked polyethylene (HXLPE) liners to reduce the clinical incidence of osteolysis, it is not known if the improved wear resistance will outweigh the inflammatory potential of HXLPE wear debris generated in vivo. " 02/01/2006 - "Periacetabular and femoral osteolysis in group 1 was significantly greater than group 2. In conclusion, the method of sterilization might have influenced the outcome of Hylamer polyethylene liners." 05/01/1996 - "The prevalence of osteolysis was also significantly greater in acetabular components with an outer diameter of fifty-five millimeters or less (a polyethylene thickness of 8.5 millimeters or less) (p = 0.03). " 10/01/1995 - "Thirteen patients in this series had radiologic osteolysis and a significantly greater femoral head displacement and polyethylene volumetric wear than those with no osteolysis. " 02/01/2013 - "The introduction of this HXLPE substantially improved the prognosis of patients after THA up to 13 years as judged by clinical scores, incidence of osteolysis, and polyethylene wear measurements. "
2.	Pathologic Constriction (Stenosis) 12/01/1998 - "To induce cerebral hypoperfusion, chronic stenosis was produced by placing a 3 mm long polyethylene cuff around the bilateral carotid arteries of normotensive Wistar rats (Wistar) and spontaneously hypertensive rats (SHR). " 08/01/1993 - "The therapeutic armamentarium for treating peptic strictures has greatly expanded during the past 30 yr. It now includes potent anti-secretory medications, bougienage with flexible polyethylene dilators or balloons, and anti-reflux surgery. " 01/01/1984 - "For bilio-nasal drainage a 250-cm- long preformed polyethylene tube is placed above the stenosis to provide the flow out of the congested bile duct. " 01/01/1971 - "[Use of a hollow needle to guide a polyethylene thread into the lacrimal canal during its stricture]." 04/01/1955 - "[Stenosis of the hepatic duct treated by excision and repair with a polyethylene tube; results after 2 years]."
3.	Neoplasms (Cancer) 04/01/2013 - "Polyethylene glycolated nanoliposomes with a size range up to 200 nm are suitable for encapsulation of cytotoxic drugs and can target tumors passively through the enhanced permeation and retention effect. " 01/01/2012 - "DOG1, CD117 and PDGFRA were detected with IHC Envision ldpe-g-nvp in 63 GISTs and 43 cases of non-GISTs, and analyzed for relations with clinicopathological factors (gender, age, location, tumor size, mitotic phase, histology) and risk degree. " 09/01/2010 - "Biologic reaction to polyethylene wear particles had then produced the extensile osteolytic lesion extending to the extramedullary diaphysis of the femur that presented as a solitary thigh mass mimicking a soft tissue tumor. " 05/01/2006 - "The indications for application of porous polyethylene implants in our clinic were congenital malformations (15), post-traumatic defects (10), and reconstructions after tumor resection (2). " 02/01/2003 - "Polyethylene sheath device to reduce tumor cell seeding along the needle tract in percutaneous biopsy."
4.	Dislocations 06/01/2004 - "Despite improved scratch resistance of ceramic-bearing surfaces, irregularities introduced by metallic deposition after recurrent dislocation can damage a highly cross-linked polyethylene liner." 11/01/2007 - "Designing polyethylene liners with a sufficiently deep articular surface that exceeds 0.95 mm may prove beneficial for decreasing the prevalence of early dislocation, independent of impingement damage." 09/01/2005 - "The objective of this study was to evaluate the efficacy of an anti-dislocation posterior elevated rim polyethylene liner on long-term dislocation rate and wear. " 12/01/2015 - "The purpose of this study was to use a national registry to assess whether the choice of bearings-metal-on-polyethylene (MoP), ceramic-on-polyethylene (CoP), ceramic-on-ceramic (CoC), or metal-on-metal (MoM)-is associated with differences in the risk of late dislocation. " 06/01/2013 - "This study evaluated Kaplan-Meier survival, revisions for dislocation, and cost of MOM THA compared with metal-on-cross-linked polyethylene (MOXP) THA in a community joint registry, with subset analysis of the recalled Depuy ASR™ implant. "
5.	Infection 12/01/1985 - "During preliminary studies, it was demonstrated that separation of polyethylene antimicrobial incise drapes from the skin during operation was associated with a sixfold increase in infection rate when compared with operations in which the incise drape did not lift. " 09/01/2015 - "Complications following joint replacement surgery include aseptic or mechanical loosening, as well as polyethylene wear and prosthetic joint infection. " 09/01/2015 - "In the construction of artificial hip joint replacements, the surface and substrate of a cross-linked polyethylene (CLPE) liner are designed to achieve high wear resistance and prevent infection by bacteria. " 06/01/2015 - "Some recently debated diagnoses like low-grade-infection showed a high increase in incidence whereas classic failure mechanisms like polyethylene wear showed a decrease over the time. " 02/01/2015 - "MRI can reliably predict the presence and extent of infection, component loosening and polyethylene wear, and component malrotation, and it can evaluate the integrity of surrounding soft tissue structures. "

Related Drugs and Biologics

1.	Permethrin (Ambush)
2.	Aluminum Oxide (Sapphire)
3.	Titanium
4.	ultra-high molecular weight polyethylene (UHMWPE)
5.	Plastics
6.	Cobalt
7.	Silicones
8.	Chromium
9.	Interleukin-2 (IL2)
10.	Polyethylene Glycols (Polyethylene Glycol)

Related Therapies and Procedures

1.	Stents
2.	Arthroplasty
3.	Prostheses and Implants (Prosthesis)
4.	Transplants (Transplant)
5.	Bone Transplantation (Bone Grafting)