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Natural Cytotoxicity Triggering Receptors

A subclass of natural killer cell receptors that perform an important role in the recognition of tumor cells by NK CELLS.

Also Known As:

Receptors, Natural Cytotoxicity Triggering

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Natural Killer Cell Receptors: 407
        Natural Cytotoxicity Triggering Receptors: 1
        Natural Cytotoxicity Triggering Receptor 1: 36
        Natural Cytotoxicity Triggering Receptor 3: 24
        Natural Cytotoxicity Triggering Receptor 2: 11

Experts

1.	Bi, Yu-Fang: 1 article (01/2020)
2.	Chen, Yao: 1 article (01/2020)
3.	Cui, Xiu-Liang: 1 article (01/2020)
4.	Fu, Jing: 1 article (01/2020)
5.	He, Jia: 1 article (01/2020)
6.	Li, Mian: 1 article (01/2020)
7.	Ning, Guang: 1 article (01/2020)
8.	Qin, Wen-Hao: 1 article (01/2020)
9.	Qin, Ying-Yi: 1 article (01/2020)
10.	Shen, Feng: 1 article (01/2020)

Related Diseases

1.

Hepatocellular Carcinoma (Hepatoma)

01/01/2020 - "NK cells isolated from C57BL/6J mice fed with HCD had increased expression of NK cell-activating receptors (natural cytotoxicity triggering receptor 1 and natural killer group 2, member D), markers of effector function (granzyme B and perforin), and cytokines and chemokines compared with NK cells from mice on ND; these NK cells also had enhanced cytotoxic activity against mouse hepatoma cells, accumulated cholesterol, increased lipid raft formation, and immune signaling activation. "

Related Drugs and Biologics

1.	Perforin
2.	Granzymes (Granzyme)
3.	Chemokines
4.	Cytokines
5.	Lipids
6.	Cholesterol