Glyphosate (Roundup)

Active compound in herbicidal formulations that inhibits 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE.

Also Known As:

Roundup; Kalach 360 SL; N-(phosphonomethyl)glycine; Gliphosate; Glyphosate Hydrochloride (2:1); Glyphosate, Calcium Salt; Glyphosate, Calcium Salt (1:1); Glyphosate, Copper (2+) Salt; Glyphosate, Dilithium Salt; Glyphosate, Disodium Salt; Glyphosate, Magnesium Salt; Glyphosate, Magnesium Salt (2:1); Glyphosate, Monoammonium Salt; Glyphosate, Monopotassium Salt; Glyphosate, Monosodium Salt; Glyphosate, Sodium Salt; Glyphosate, Zinc Salt; Yerbimat

Networked: 553 relevant articles (6 outcomes, 95 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Mesnage, Robin: 11 articles (01/2022 - 03/2012)
2.	Antoniou, Michael N: 8 articles (01/2022 - 02/2016)
3.	Mohamed, Fahim: 6 articles (01/2021 - 09/2009)
4.	Chun, Byeong Jo: 6 articles (01/2019 - 01/2006)
5.	Moon, Jeong Mi: 6 articles (01/2019 - 01/2006)
6.	Séralini, Gilles-Eric: 6 articles (08/2018 - 01/2009)
7.	Belpoggi, Fiorella: 5 articles (01/2022 - 01/2016)
8.	Mandrioli, Daniele: 5 articles (01/2022 - 01/2016)
9.	McCall, William V: 5 articles (12/2021 - 01/2020)
10.	Beane Freeman, Laura E: 5 articles (10/2020 - 01/2018)

Related Diseases

1.	Poisoning 04/01/2023 - "This case report highlights the life-threatening nature of glyphosate poisoning. " 04/01/2023 - "The capillary-leakage syndrome caused by glyphosate poisoning: a case report." 12/01/2022 - "Glyphosate is generally considered to be less toxic or even safe for mammals, including humans, and most patients with glyphosate poisoning have a better prognosis. " 07/04/2022 - "In our retrospective study of acute glyphosate poisoning, we examined records from the French National Database of Poisonings, dated between January 1, 2004, and December 31, 2016. " 01/01/2022 - "Results: The chronic roundup poisoning was accompanied by impaired state of vegetative nervous system that revealed itself in the growing indices of variation pulsometry: tension index - 1.6 times (P<0.001), index of regulatory system activity - 1.52 times (P<0.001), vegetative balance index - 2.36 times (P<0.001), rhythm vegetative index - 1.39 times (P<0.001). "
2.	Neoplasms (Cancer) 11/01/2023 - "We found that few studies have been published on glyphosate, and that the largest number of publications are from the International Agency for Research on Cancer classification to date. " 11/01/2023 - "In this review, we investigate the association between glyphosate and cancer risk and found that most of the studies focused using animals showing negative effects such as genotoxicity, cytotoxicity and neurotoxicity, some studies used cancer cell lines showing proliferative effects due to glyphosate exposure. " 01/01/2023 - "This work aimed to review glyphosate occurrence and exposure since 2015 up to date, considering studies associated with either environmental or occupational exposure and the epidemiological assessment of cancer risk in humans. " 01/01/2022 - "Most existing studies on health effects of glyphosate have focused on occupational settings and cancer outcomes and few have examined this common exposure in relation to the health of pregnant women and newborns in the general population. " 12/01/2020 - "Considering analyses of the individual studies, the consistency of the data across studies, the pooled analyses, the historical control data, non-neoplastic lesions, mechanistic evidence and the associated scientific literature, the tumor increases seen in this review are categorized as to the strength of the evidence that glyphosate causes these cancers. "
3.	Body Weight (Weight, Body) 10/01/2011 - "biloba provided significant protection against glyphosate-induced toxicity, and the strongest effect was observed at a dose of 150 mg/kg of body weight. " 01/01/2021 - "Measurements of glyphosate in urine can also be used to estimate ingested glyphosate exposure, and studies indicate that exposure is <3% of the current European ADI for glyphosate, which is 0.5 mg glyphosate/kg body weight. " 02/01/2018 - "We found that glyphosate as well as the commercial formulation Glyfonova®450 PLUS administered at up to fifty times the established European Acceptable Daily Intake (ADI = 0.5 mg/kg body weight) had very limited effects on bacterial community composition in Sprague Dawley rats during a two-week exposure trial. " 12/20/2023 - "Here, we explored the impact of maternal oral glyphosate exposure (0.5 and 50 mg/kg body weight/day) during pregnancy and the lactational period on offspring's behavior, brain gene expression and gut microbiota using a cross-generational mouse model. " 08/18/2023 - "It was first revealed that glyphosate-induced changes in blood parameters may be related to a negative impact on the zootechnical characteristics including the digestive tract organ development and body weight gain. "
4.	Infertility (Sterility) 04/01/2022 - "Efficacy of N-acetyl- l-cysteine against glyphosate induced oxidative stress and apoptosis in testicular germ cells preventing infertility." 09/05/2017 - "The incidence of infertility in human is on the increase and the use of Roundup herbicide and presence of its residues in foodstuff is a major concern. " 01/01/2020 - "Recent studies have demonstrated a relationship between glyphosate exposure and a number of disorders such as cancer, immune and metabolic disorders, endocrine disruption, imbalance of intestinal flora, cardiovascular disease, and infertility; these results have given glyphosate a considerable amount of media and scientific attention. " 12/01/2013 - "Reproductive issues associated with celiac disease, such as infertility, miscarriages, and birth defects, can also be explained by glyphosate. " 10/05/2017 - "Glyphosate [N-phosphono-methylglycine (PMG)] is the most used herbicide worldwide and it has been reported very recently that Glyphosate is very harmful and can produce lots of diseases such as alzheimer and parkinson's disease, depression, cancer, infertility including genotoxic effects. "
5.	Pyloric Stenosis 07/01/2019 - "Timely and effective treatment of pyloric stenosis caused by glyphosate poisoning is important. " 07/01/2019 - "Pyloric stenosis due to glyphosate poisoning in a 36-year-old man. " 07/01/2019 - "Surgical treatment of pyloric stenosis caused by glyphosate poisoning: A case report." 07/01/2019 - "Gastrectomy is necessary to treat pyloric stenosis caused by glyphosate poisoning." 08/01/2020 - "Glyphosate-induced Delayed Pyloric Obstruction, Ulcer and Scar Changes."

Related Drugs and Biologics

1.	Diquat
2.	Antidotes
3.	DNA (Deoxyribonucleic Acid)
4.	5-Methylcytosine (5 Methylcytosine)
5.	Peptides (Polypeptides)
6.	Acetylcysteine (Siran)
7.	Herbicides
8.	Glyphosate (Roundup)
9.	Surface-Active Agents (Surfactants)
10.	aminomethylphosphonic acid (AMPA)

Related Therapies and Procedures

1.	Therapeutics
2.	Length of Stay
3.	Renal Dialysis (Hemodialysis)
4.	Vagus Nerve Stimulation
5.	Transcranial Magnetic Stimulation