Amino Acids

05/01/2014 - "In this work, we have designed a novel cationic peptide of 27 amino acids (Cypep-1), which shows efficacy against a number of cancer cell types, both in vitro and in vivo, while normal human fibroblasts were significantly less affected. "
06/01/1997 - "Two-dimensional correlated MR spectroscopic data revealed that a variety of amino acids have a significantly greater likelihood of being detected in tumor than in normal tissues. "
11/01/2015 - "At present, PET studies using radiolabeled amino acids appear to improve clinical decision-making as these tracers can offer better delineation of tumor extent as well as improved targeting of biopsies, surgical interventions, and radiation therapy. "
06/01/1996 - "These results indicate that amino acids 211-214, which may form a turn region, constitute a major recognition site for pAb1, and this structure may also be involved in the cell cycle-dependent modification of TK1, pAb1 is a very useful tool for studies of the cell cycle regulation of TK1, and it may be used to identify and quantify rapidly proliferating cells such as tumor cells."
08/01/2006 - "Recently, promising results concerning uptake in vivo in tumors of D-amino acids have been published. "

09/01/2015 - "This retrospective analytical study showed that females had small but significantly higher levels of amino acids and the correction for body weight amplified these differences. "
11/01/2007 - "The objective of this study was to evaluate the effect of early post-hatch levels of dietary amino acids+/-0.88 NRC, 1.00 NRC, and 1.12 NRC), and feed deprivation on the satellite cell mitotic activity, pectoralis thoracicus muscle weight, and body weight of male turkeys (Meleagris gallopavo). "
03/01/2006 - "In contrast to calves weighing less than 100 kg of body weight, heavy preruminant calves do not respond in protein retention to an increased intake of indispensable amino acids in dose-response studies. "
10/01/1999 - "The present studies were designed to extend this earlier observation by assessing the role of different dietary amino acids in modulation of cholesterolemic responses and body weights. "
07/25/2014 - "Chicks were first orally administered with different doses (0, 3.75, 7.5 and 15 mmol/kg body weight) of L- or D-Asp to monitor the effects of these amino acids on rectal temperature during 120 min of the experimental period. "

09/01/1982 - "Supplementation with both amino acids, however, significantly improved both weight gain and PER. "
01/01/1975 - "A growth assay, using diets formulated on the results of these assays, showed that the available amino acid profile obtained from the CONV assay resulted in significantly improved weight gains and feed conversions as compared to a similar diet based on the chemical analysis of amino acids alone. "
06/01/2009 - "A prospective strategy of EAA in preterm infants <1500 g was associated with an improved weight gain, suggesting that nutrition that included amino acids may be critical during the first 24 h of life."
07/01/1991 - "Increasing all indispensable amino acids by 20% from their original levels improved weight gain and gain:feed ratio to levels equivalent to those of pigs fed a 20% protein corn-soybean meal-dried whey positive control diet. "
09/01/2009 - "2. Decreases of up to 15% of NRC recommendations in these three amino acids did not affect feed intake, weight gain and gain:feed intake values in the 15-35- and 15-42-d feeding periods. "

07/01/2008 - "Immunizing mice with either the N1N2N3 (amino acids 50 to 597) or N2N3 (amino acids 273 to 597) subdomain of the N-terminal A domain of recombinant SdrG (rSdrG) elicited a robust antibody response; however, only mice vaccinated with rSdrG(N23) exhibited a significant reduction in 0-47 recovered after experimental infection. "
10/01/2011 - "Finally, to investigate the potential utility of D-amino acids in preventing device-related infections, we have shown that surfaces impregnated with D-amino acids were effective in preventing biofilm growth."
06/01/2015 - "Our previous studies demonstrated that the enterovirus 71 (EV71) virus-like particle (VLP) produced from yeast is a vaccine candidate against EV71 infection and that a chimeric EV71/coxsackievirus A16 (CVA16) VLP with the replacement of 4 amino acids in the VP1 GH loop can confer protection against both EV71 and CVA16 infections. "
01/01/1976 - "II. Postoperative: Interruption of the vicious circle of diminished offer of nutrition, postoperative katabolism, which increases the need for amino-acids and so interferes with the process of wound-healing and the protection against infection."
08/01/2015 - "In this study, we showed that a mutant pUL38 lacking the N-terminal 24 amino acids (pHA-UL3825-331) was fully functional in suppressing cell death during infection. "

11/15/2014 - "After the addition of amino acids to the starvation condition, a similar quick signal appeared by significant reduction of the LC3 ratio and bulk proteolysis. "
11/19/2004 - "In contrast, human I-1alpha, which lacks amino acids 83-134, and I-1 with C-terminal deletions were significantly less effective in promoting yeast growth under starvation conditions. "
05/01/2004 - "The synthesis of ppGpp in the relA gene-disrupted mutant was completely eliminated under conditions of starvation for amino acids, whereas synthesis persisted, but was greatly reduced in the rsh gene-disrupted mutant. "
05/01/2009 - "Our recent study suggests that the autophagy response to starvation, previously thought to be cell-autonomous, can be systemically regulated, and that there is a specific sensor for monitoring systemic amino acids levels in Caenorhabditis elegans."
11/01/2008 - "We used an unbiased quantitative proteomics approach relying on stable isotope labeling by amino acids in cell culture (SILAC) to study global protein dynamics during amino acid starvation-induced autophagy. "