Netrin Receptors

Cell surface receptors that bind NETRINS. They typically contain both IMMUNOGLOBULIN DOMAINS and FIBRONECTIN TYPE III DOMAINS and function to mediate CELL MIGRATION and AXON GUIDANCE.

Also Known As:

Networked: 84 relevant articles (0 outcomes, 9 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Mehlen, Patrick: 6 articles (01/2021 - 04/2003)
2.	Xiong, Wen-Cheng: 6 articles (01/2021 - 11/2004)
3.	Mei, Lin: 5 articles (01/2021 - 11/2004)
4.	Kennedy, Timothy E: 4 articles (01/2021 - 12/2006)
5.	Tessier-Lavigne, Marc: 4 articles (12/2014 - 10/2007)
6.	Gibert, Benjamin: 3 articles (01/2021 - 12/2013)
7.	Paradisi, Andrea: 3 articles (12/2013 - 10/2008)
8.	Kennedy, T E: 3 articles (08/2010 - 03/2001)
9.	Xie, Yi: 3 articles (02/2007 - 11/2004)
10.	Ahmed, Giasuddin: 2 articles (01/2021 - 09/2011)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 05/26/2018 - "Purpose: In the present study, we evaluated the role of promoter hypermethylation of UNC5C gene (one of the netrin-1 receptors) in colorectal cancer patients of Kashmiri population (North India). " 08/02/2017 - "Studies published early this year provide evidence that in humans, Netrin receptor, Deleted in Colorectal Cancer (DCC), is a master regulator of axonal crossing throughout the neuraxis." 03/28/2017 - "Immunoprecipitation studies identified 3 targets, including the Netrin-1 receptors DCC (deleted in colorectal carcinoma) and UNC5A (uncoordinated-5A) as well as Caspr2 (contactin-associated protein-like 2). " 01/01/2022 - "Expression of the netrin-1 receptors deleted in colorectal cancer (DCC) and uncoordinated 5 homolog (UNC5H) is frequently silenced in colorectal cancer (CRC) by either loss of heterozygosity or epigenetic mechanisms. " 01/01/2021 - "NEO1, a member of deleted in colorectal cancer (DCC) family netrin receptors, was reduced in brain samples of patients with MMD. "
2.	Thymoma (Thymic Carcinoma) 03/28/2017 - "This study provides Class III evidence that antibodies against Netrin-1 receptors can identify patients with thymoma (sensitivity 21.4%, specificity 100%)." 03/28/2017 - "Antibodies against Netrin-1 receptors (DCC and UNC5a) and Caspr2 often coexist and associate with thymoma in patients with neuromyotonia and myasthenia gravis. "
3.	Osteoarthritis 06/01/2022 - "This study aims to define serum levels of netrin-1 and netrin receptors in patients with fibromyalgia (FM) and osteoarthritis (OA). " 06/01/2022 - "Serum netrin-1 and netrin receptor levels in fibromyalgia and osteoarthritis."
4.	Fibromyalgia (Fibrositis) 06/01/2022 - "This study aims to define serum levels of netrin-1 and netrin receptors in patients with fibromyalgia (FM) and osteoarthritis (OA). " 06/01/2022 - "Serum netrin-1 and netrin receptor levels in fibromyalgia and osteoarthritis."
5.	Neoplasms (Cancer) 12/06/2022 - "A Systematic Analysis of the Role of Unc-5 Netrin Receptor A (UNC5A) in Human Cancers." 06/14/2011 - "The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor." 10/01/2009 - "Interfering with multimerization of netrin-1 receptors triggers tumor cell death." 01/01/2009 - "In addition, the expression of the netrin receptor UNC5B was induced and that of UNC5C was reduced in the tumor cells. " 04/01/2003 - "The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment."

Related Drugs and Biologics

1.	Netrin-1
2.	Netrins
3.	neogenin
4.	Adenosine A2B Receptor
5.	Complementary DNA (cDNA)
6.	Myosins (Myosin)
7.	Antibodies
8.	netrin-2
9.	Proteins (Proteins, Gene)
10.	netrin-3

Related Therapies and Procedures

1.	Microspheres (Microsphere)