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Microspheres (Microsphere)

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Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.

Also Known As:

Microsphere; Microbead; Latex Beads; Microbeads; Bead, Latex; Beads, Latex; Latex Bead; Latex Particle; Latex Sphere; Particle, Latex; Particles, Latex; Sphere, Latex; Spheres, Latex; Latex Particles; Latex Spheres

Networked: 4540 relevant articles (311 outcomes, 586 trials/studies)

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Therapy Context: Research Results

Equipment and Supplies
- Microspheres: 4540

Experts

1.	Salem, Riad: 54 articles (12/2015 - 06/2002)
2.	Lewandowski, Robert J: 33 articles (12/2015 - 12/2005)
3.	Tabata, Yasuhiko: 31 articles (08/2014 - 04/2002)
4.	Takeo, Satoshi: 23 articles (01/2011 - 01/2002)
5.	Takagi, Norio: 22 articles (05/2013 - 01/2002)
6.	Gates, Vanessa L: 19 articles (12/2015 - 06/2002)
7.	Kennedy, Andrew S: 19 articles (12/2015 - 02/2003)
8.	Ryu, Robert K: 17 articles (03/2014 - 02/2007)
9.	Sangro, Bruno: 16 articles (06/2015 - 11/2006)
10.	Sato, Kent T: 16 articles (03/2014 - 02/2007)

Related Diseases

1.	Neoplasms (Cancer) 06/01/2004 - "These radiolabeled microspheres are very stable and have a proven efficacy in the field of primary as well as metastatic cancers. " 05/01/1998 - "Microsphere injection caused a marked decrease of tumor blood flow and pH. During heating, there was a marked increase of the maximum temperature in tumor tissue compared with normal muscle. " 10/01/2011 - "Reestablishment of intrahepatic arterial inflow to hepatic tumors by embolization of parasitized EHAs is safe and effective and results in successful delivery of yttrium-90 microspheres to tumors previously perfused by parasitized EHAs." 05/07/2010 - "In vitro, cancer cells incubated with PTX/HAuNS-loaded microspheres and irradiated with NIR light display significantly greater cytotoxic effects than cells incubated with the microspheres alone or cells irradiated with NIR light alone, owing to NIR-light-triggered drug release. " 04/01/2010 - "These ceramic microspheres were remarkably embolized in tumor microvessels as well as in the feeding arteries and a significant reduction of intratumoral vascularity was also demonstrated following treatment with TNP-470-loaded microspheres. "
2.	Hepatocellular Carcinoma (Hepatoma) 02/01/2000 - "To observe the therapeutic efficacy of microsphere-entrapped Curcuma aromatica oil (MS-CAO) infused via hepatic artery against transplanted hepatoma in rats. " 02/01/2000 - "[Therapeutic efficacy of microsphere-entrapped curcuma aromatica oil infused via hepatic artery against transplanted hepatoma in rats]." 01/01/2015 - "Available data on the use of (90)Y-glass microspheres in hepatocellular carcinoma and metastatic disease indicate that this treatment is safe and effective. " 08/01/2010 - "Intraarterial delivery of yttrium-90 ((90)Y)-bound microspheres (ie, radioembolization) is a promising treatment for hepatocellular carcinoma (HCC). " 12/01/2013 - "Transarterial chemoembolization using microspheres is a new treatment option for patients with hepatocellular carcinoma. "
3.	Neoplasm Metastasis (Metastasis) 08/01/2013 - "Six months after the treatment the patient reported a complete remission of tumour areas which received a high radiation dose, while progression of metastases was observed in the area that presented scarce microsphere localization at (90)Y PET. " 04/01/2014 - "Repeated bland-TAE using 100-μm microspheres injected via an implantable port-catheter system could be effective for liver metastases, although the caution of biliary injury is needed." 04/01/2007 - "This case illustrates the utility of FDG PET in the assessment of the therapeutic efficacy of 90Y microspheres in colorectal hepatic metastases." 04/01/2010 - "This study assessed the efficacy of (90)Y microsphere therapy for patients with unresectable neuroendocrine tumour liver metastases (NETLMs). " 05/01/2009 - ": The objective of the current study was to determine the safety and efficacy of Yttrium-90 (Y90) microsphere treatment in patients with liver-dominant colorectal metastases. "
4.	Infection 01/01/2015 - "Further understanding the underlying egg-microsphere interactions would enable a targeted optimisation of egg-particle binding and may thus enable a significant improvement of the Helmintex™ method and diagnostic sensitivity in areas with low infection rates. " 01/15/2014 - "The antibiotic microspheres successfully prevented infection in 100% of the eleven limbs with treated implants, which represented a significant improvement (p = 0.004) compared with the infection rate of 64% (seven of eleven) for the limbs with control implants. " 01/01/1991 - "Mares classified as potentially susceptible to chronic uterine infections demonstrated a significant delay in physical clearance of microspheres from the uterus compared to the resistant mares (P less than 0.0001). " 11/01/2009 - "In the present study, we established and validated a multiplex microbead immunoassay (MIA) for surveillance of Cryptosporidium parvum infections. " 01/01/2009 - "This study reports differences in the prevalence of infections with all four human malarial species and of mixed infections as diagnosed by LM and post-PCR ligase detection reaction-fluorescent microsphere (LDR-FMA) assay in 15 villages in the central Sepik area of Papua New Guinea. "
5.	Ischemia 10/01/1980 - "Thus, this autoradiographic method using 99mTc-labeled human albumin microspheres is useful in delineating the area of ischemia after coronary artery occlusion and in evaluating the efficacy of pharmacologic agents designed to protect ischemic myocardium. " 06/01/1993 - "We produced an improved microembolism model of cerebral focal ischemia by injection of 1000-2000 microspheres (50 +/- 5 microns diameter) via a tube retrogradely inserted into the right external carotid artery in freely moving rats. " 03/22/2005 - "Similarly, TG mice were more resistant to the inhibitory effect of ADMA on angioadaptation (angiogenesis and arteriogenesis) after hindlimb ischemia, as assessed by fluorescent microsphere studies and postmortem microangiograms. " 10/01/1999 - "Reperfusion pattern of the immature femoral head after critical ischemia: a microsphere study in pigs." 07/01/1999 - "The correlation between the CT and the microsphere measurements was good for both normal and ischemia studies (r > 0.78, slope > 0.9). "

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3.	Antigens
4.	Doxorubicin (Adriamycin)
5.	Polymers
6.	Gelatin
7.	Minocycline (Cyclops)
8.	Chitosan
9.	Carbon Monoxide
10.	alginic acid (sodium alginate)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Injections
3.	Microspheres (Microsphere)
4.	Transplantation (Transplant Recipients)
5.	Root Planing