Punctal Plugs

Small devices that are inserted into the tear ducts (NASOLACRIMAL DUCTS). They are used to block the drainage of TEARS for the treatment of DRY EYE SYNDROMES.

Also Known As:

Collagen Punctal Plugs; Silicone Punctal Plugs; Collagen Punctal Plug; Plug, Collagen Punctal; Plug, Punctal; Plug, Silicone Punctal; Plugs, Collagen Punctal; Plugs, Punctal; Plugs, Silicone Punctal; Punctal Plug; Punctal Plug, Collagen; Punctal Plug, Silicone; Punctal Plugs, Collagen; Punctal Plugs, Silicone; Silicone Punctal Plug

Networked: 162 relevant articles (32 outcomes, 20 trials/studies)

Relationship Network

Therapy Context: Research Results

Equipment and Supplies
- Prostheses and Implants: 21690
  - Punctal Plugs: 162

Experts

1.	Tsubota, Kazuo: 8 articles (10/2015 - 01/2009)
2.	Dogru, Murat: 6 articles (02/2014 - 01/2009)
3.	Kinoshita, Shigeru: 5 articles (01/2018 - 06/2002)
4.	Komuro, Aoi: 4 articles (01/2018 - 06/2002)
5.	Yokoi, Norihiko: 4 articles (01/2018 - 06/2002)
6.	Ervin, Ann-Margret: 3 articles (01/2019 - 09/2010)
7.	Toda, Ikuko: 3 articles (11/2018 - 03/2007)
8.	Tong, Louis: 3 articles (10/2017 - 01/2016)
9.	Boldin, Ingrid: 3 articles (05/2013 - 09/2007)
10.	Horwath-Winter, Jutta: 3 articles (05/2013 - 09/2007)

Related Diseases

1.	Dry Eye Syndromes (Dry Eye Syndrome) 03/01/2004 - "Punctal occlusion using punctal plugs is very effective for the treatment of tear-deficient dry eye. " 03/01/2011 - "To report the rate of recanalization and the efficacy of punctal occlusion surgery with a high heat-energy-releasing cautery device in patients with severe dry eye disease and recurrent punctal plug extrusion. " 07/01/1989 - "Punctal plug insertion is therapeutic for dry eye disease, but extrusion is a significant problem." 08/01/2015 - "These data will allow us to guide patient decision making for the safe and effective treatment of punctal plugs for moderate to severe dry eye." 01/01/2022 - "Our study revealed that dry eye symptoms and signs, including meibomian gland function, improved for at least 6 months in non-SS dry eye patients as well as in SS dry eye patients after punctal plugs insertion."
2.	Pathologic Constriction (Stenosis) 07/01/2015 - "Perforated punctal plugs are found convenient and effective in managing punctal stenosis." 03/01/2021 - "Perforated punctal plugs and three-snip punctoplasty are safe and effective in treatment of punctal stenosis. " 04/20/2023 - "All eyes had either punctal plugs, cauterized puncta, or punctal and (or) canaliculus stenosis. " 01/01/2022 - "Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography after Punctal Dilation Versus Punctal Plug Insertion in Cases of Inflammatory Punctual Stenosis." 10/03/2021 - "Evaluation of the patency and position of perforated lacrimal punctal plugs implanted for treating punctal stenosis together with quantitative assessment of the precorneal tear film using anterior segment optical coherence tomography (AS-OCT). "
3.	Inflammation (Inflammations) 11/01/2018 - "The first and most important misconception is that ocular surface inflammation should be sufficiently controlled before punctal plug insertion. " 01/17/2022 - "Punctal plug insertion, primarily targeting aqueous deficiency, is the mainstay of the treatment for dry eye in primary Sjögren's syndrome even in the presence of ocular surface inflammation. " 04/01/2010 - "No cases of spontaneous punctal plug migration, stent displacement, eyeball irritation or inflammation, or granuloma formation were encountered. " 02/01/2021 - "Safety and efficacy of nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery." 01/01/2021 - "Reply to comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery."
4.	Pain (Aches) 02/01/2021 - "Safety and efficacy of nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery." 01/01/2021 - "Reply to comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery." 01/01/2021 - "Comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery." 10/01/2018 - "A 48-year-old female with a 10-year history of rheumatoid arthritis under systemic immunomodulation developed non-resolved severe ocular dryness, pain, photophobia and blurred vision due to corneal epithelial keratopathy OD much worse than OS despite topical artificial tears, steroids, cyclosporine, autologous serum drops, punctal plugs and scleral lens for the last 3 years. "
5.	Cataract (Cataracts) 02/01/2021 - "To evaluate the safety and efficacy of a nepafenac punctal plug delivery system (N-PPDS) after cataract surgery. " 02/01/2021 - "Safety and efficacy of nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery." 01/01/2021 - "Reply to comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery." 01/01/2021 - "Comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery."

Related Drugs and Biologics

1.	Lubricant Eye Drops (Artificial Tears)
2.	nepafenac (Nevanac)
3.	Ophthalmic Solutions (Eye Drops)
4.	Silicones
5.	Silicon
6.	Type A Botulinum Toxins (Botox)
7.	atelocollagen
8.	Povidone-Iodine (Betadine)
9.	Iodine
10.	Monoclonal Antibodies

Related Therapies and Procedures

1.	Cautery
2.	Laser In Situ Keratomileusis (LASIK)
3.	Drug Therapy (Chemotherapy)
4.	Punctal Plugs
5.	Therapeutics