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14,21- dihydroxydocosa- 4,7,10,12,16,19- hexaenoic acid

promotes prohealing functions of macrophages; structure in first source

Also Known As:

14,21-diHDHA; 14S,21R-dihydroxydocosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793

Experts

1.	Hong, Song: 2 articles (10/2011 - 02/2011)
2.	Lu, Yan: 2 articles (10/2011 - 02/2011)
3.	Shah, Shraddha P: 2 articles (10/2011 - 02/2011)
4.	Tian, Haibin: 2 articles (10/2011 - 02/2011)

Related Diseases

1.	Wounds and Injuries (Trauma) 10/01/2011 - "Impaired macrophage functions imposed by diabetic complications and the suppressed formation of 14S,21R-dihydroxydocosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid (14S,21R-diHDHA) in wounds contribute significantly to deficient wound healing in diabetics, but how are macrophage functions and 14S,21R-diHDHA formation associated? " 02/11/2011 - "Here, we identified suppressed formation of a novel reparative lipid mediator 14S,21R-dihydroxydocosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid (14S,21R-diHDHA) in cutaneous wounds of diabetic db/db mice. "
2.	Diabetes Complications 10/01/2011 - "Impaired macrophage functions imposed by diabetic complications and the suppressed formation of 14S,21R-dihydroxydocosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid (14S,21R-diHDHA) in wounds contribute significantly to deficient wound healing in diabetics, but how are macrophage functions and 14S,21R-diHDHA formation associated? "
3.	Asthma (Bronchial Asthma) 03/01/2024 - "Thirty-one characteristic lipids and fatty acids of asthma were screened by machine-learning random forest model based on serum lipidome data, and the alterations of inflammatory characteristic lipids and fatty acids including palmitic acids, 12,13-DiHODE, 14,21-DiHDHA, prostaglandin D2 and LysoPA(18:2) showed significant correlated with high serum levels of MMP, TPP and TNBP. "

Related Drugs and Biologics

1.	Lipids
2.	Matrix Metalloproteinases (MMPs)
3.	Prostaglandin D2
4.	Palmitic Acids
5.	Fatty Acids (Saturated Fatty Acids)