Secundum Type Atrial Septal Defect

A heterogeneous group of atrial heart septal defects (ASD) that occurs both sporadically and in families (OMIM: 108800). Conduction defects or non-cardiac abnormalities may or may not be present. In familial cases, genes have been mapped and mutations identified for several types, including a mutation in the GATA4 gene for ASD2 (OMIM: 607941).

Also Known As:

Networked: 19 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Tachycardia (Tachyarrhythmias)
2.	Dextrocardia
3.	Pulmonary Valve Stenosis (Pulmonary Stenosis)
4.	Ventricular Heart Septal Defects (Ventricular Septal Defect)
5.	Congenital Heart Defects (Congenital Heart Defect)

Experts

1.	Meriç, Murat: 1 article (10/2018)
2.	Yüksel, Serkan: 1 article (10/2018)
3.	Bai, Yuan: 1 article (01/2015)
4.	Ding, Xue-Yan: 1 article (01/2015)
5.	Liu, Su-Xuan: 1 article (01/2015)
6.	Qin, Yong-Wen: 1 article (01/2015)
7.	Xu, Xu-Dong: 1 article (01/2015)
8.	Zhao, Xian-Xian: 1 article (01/2015)
9.	Botto, Lorenzo D: 1 article (01/2014)
10.	Browne, Marilyn L: 1 article (01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Secundum Type Atrial Septal Defect:

1.	Troponin IIBA 11/01/2001 - "Elevated cardiac troponin I following heavy-resistance exercise in ostium secundum type-atrial septal defect."
2.	Deoxycytidine Monophosphate (DCMP)IBA 07/01/1998 - "According to the clinical and laboratory findings, congenital hypothyroidism, dilated cardiomyopathy (DCMP), atrioventricular complete heart block and secundum type atrial septal defect were diagnosed."
3.	BilirubinIBA 01/01/2023 - "The relationship between echocardiographic parameters and albumin bilirubin (ALBI) score in patients with isolated secundum type atrial septal defect."
4.	AlbuminsIBA 01/01/2023 - "The relationship between echocardiographic parameters and albumin bilirubin (ALBI) score in patients with isolated secundum type atrial septal defect."
5.	butalbitalFDA LinkGeneric 01/01/2014 - "Of 30 specific defect groups evaluated, adjusted odds ratios for maternal periconceptional butalbital use were statistically significant for 3 congenital heart defects: tetralogy of Fallot (adjusted odds ratio = 3.04; 95% confidence interval = 1.07-8.62), pulmonary valve stenosis (adjusted odds ratio = 5.73; 95% confidence interval = 2.25-14.62), and secundum-type atrial septal defect (adjusted odds ratio = 3.06; 95% confidence interval = 1.07-8.79). "

Therapies and Procedures

1.	Septal Occluder Device 09/11/2023 - "Percutaneous closure of secundum-type atrial septal defect using Amplatzer Septal Occluder is a safe and effective procedure accounting for a very low incidence of major complications in the long-term follow-up." 09/03/2010 - "To report usability, safety, and efficacy of the self-centering Solysafe Septal Occluder for transcatheter closure of secundum type atrial septal defect (ASD) in paediatric patients. " 09/11/2023 - "The goal of this single-centre study was to evaluate long-term results of percutaneous closure of secundum-type atrial septal defect using Amplatzer Septal Occluder with the follow-up to 25 years. " 09/11/2023 - "Long-term follow-up of percutaneous secundum-type atrial septal defect closure using Amplatzer Septal Occluder since 1995: a single-centre study." 02/15/2005 - "The aim of this study was to assess long-term results of percutaneous closure of secundum-type atrial septal defect (ASD II) using Amplatzer septal occluders (ASO). "
2.	Catheters 09/01/2005 - "Tricuspid valve vegetation in a chronic renal failure patient with an ostium secundum type atrial septal defect after placement of a peripheral catheter." 01/01/2013 - "Ostium secundum-type atrial septal defect closure has evolved from a surgical procedure requiring cardiopulmonary bypass to a percutaneous, catheter-based procedure usually requiring only an overnight hospital stay. " 09/01/1994 - "This report describes a 37-year-old man who had secundum type atrial septal defect, mirror-image dextrocardia, and drug-refractory atrial tachycardia, in whom catheter-mediated radiofrequency energy successfully eliminated the tachycardia without complication. " 10/01/2018 - "Total anomalous pulmonary venous return, secundum-type atrial septal defect, ventricular septal defect, and pulmonary hypertension were diagnosed by transthoracic echocardiography and catheter angiography. "
3.	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/01/1991 - "The operation of choice for correction of secundum type atrial septal defect is cardiopulmonary bypass. " 03/01/1968 - "Secundum type atrial septal defect: operation in 31 patients using cardiopulmonary bypass." 01/01/2013 - "Ostium secundum-type atrial septal defect closure has evolved from a surgical procedure requiring cardiopulmonary bypass to a percutaneous, catheter-based procedure usually requiring only an overnight hospital stay. "
4.	Prostheses and Implants (Prosthesis) 04/01/2009 - "Of the six patients diagnosed as having Brucella endocarditis, four had valvular disease, one had aortic and mitral mechanic valve prosthesis (AVR+MVR) and one had secundum type atrial septal defect. " 02/01/1995 - "We report on a 52-year-old man with a total cleft sternum associated exclusively with an ostium secundum type atrial septal defect, a large cono-ventricular septal defect and pulmonary stenosis, who underwent successful surgical repair of the congenital heart disease and of the sternal anomaly by direct approximation of the freshened sternal remnants to the midline without interposition of tissue graft or inert prosthesis. "
5.	Percutaneous Coronary Intervention 01/01/2023 - "Here, we report a pulmonary arterial hypertension patient associated with secundum-type atrial septal defect presented with ostial left main coronary artery compression caused by an enlarged pulmonary artery and treated with intravascular ultrasound-guided percutaneous coronary intervention."