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racemetyrosine

Also Known As:

SM-88

Networked: 4 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Tyrosine: 10509
        Methyltyrosines
        alpha-Methyltyrosine: 236
        racemetyrosine: 4

Experts

1.	Noel, Marcus S: 2 articles (11/2022 - 01/2020)
2.	Del Priore, Giuseppe: 2 articles (01/2021 - 01/2020)
3.	Chung, Vincent: 1 article (11/2022)
4.	Hartley, Marion L: 1 article (11/2022)
5.	Kim, Dae Won: 1 article (11/2022)
6.	Kim, Semmie: 1 article (11/2022)
7.	Ocean, Allyson J: 1 article (11/2022)
8.	Philip, Philip Agop: 1 article (11/2022)
9.	Picozzi, Vincent J: 1 article (11/2022)
10.	Staszewski, Harry: 1 article (11/2022)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "A first-in-human study of the novel metabolism-based anti-cancer agent SM-88 in subjects with advanced metastatic cancer." 01/01/2021 - "Phase II trial of SM-88, a cancer metabolism based therapy, in non-metastatic biochemical recurrent prostate cancer." 01/01/2020 - "Purpose SM-88 (D,L-alpha-metyrosine; racemetyrosine) is a novel anti-cancer agent, used with melanin, phenytoin, and sirolimus (SMK Therapy). "
2.	Adenocarcinoma 01/01/2019 - "The novel drug SM-88 seems to be a promising therapy for previously treated patients with advanced pancreatic ductal adenocarcinoma. " 11/01/2022 - "This trial explores SM-88 used with methoxsalen, phenytoin, and sirolimus (MPS) in pretreated metastatic pancreatic ductal adenocarcinoma (mPDAC) METHODS: Forty-nine patients were randomized to daily 460 or 920 mg oral SM-88 with MPS (SM-88 Regimen). "
3.	Prostatic Neoplasms (Prostate Cancer) 01/01/2021 - "Phase II trial of SM-88, a cancer metabolism based therapy, in non-metastatic biochemical recurrent prostate cancer."
4.	Pancreatic Neoplasms (Pancreatic Cancer) 11/01/2022 - "A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond."

Related Drugs and Biologics

1.	Sirolimus (Rapamycin)
2.	Phenytoin (Dilantin)
3.	Methoxsalen (Oxsoralen)
4.	racemetyrosine
5.	alpha-Methyltyrosine (Metirosine)
6.	Melanins (Melanin)

Related Therapies and Procedures

1.	Therapeutics