IDX14184
a prodrug of antiviral 2'-C-methylguanosine monophosphate; structure in first source
Also Known As:
3-hydroxy-2,2-dimethylthiopropionic acid S-(2-((5-(2-amino-6-oxo-1,6-dihydropurin-9-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-ylmethoxy)benzylaminophosphoryloxy)ethyl) ester
Networked: 1
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Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Virus Diseases (Viral Diseases)
05/01/2016
- " Single- and repeat-dose toxicity of IDX14184, a nucleotide prodrug with antiviral activity for hepatitis C viral infection, in mice, rats, and monkeys." 05/01/2016
- " The single- and repeat-dose toxicity profile of IDX14184, a novel guanosine nucleotide prodrug with antiviral activity against hepatitis C viral infection, was characterized following once daily oral administration for durations up to 13, 26, and 32 weeks in mouse, rat, and cynomolgus monkey, respectively. "
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| 2. | Hepatitis C
05/01/2016
- " Single- and repeat-dose toxicity of IDX14184, a nucleotide prodrug with antiviral activity for hepatitis C viral infection, in mice, rats, and monkeys." 05/01/2016
- " The single- and repeat-dose toxicity profile of IDX14184, a novel guanosine nucleotide prodrug with antiviral activity against hepatitis C viral infection, was characterized following once daily oral administration for durations up to 13, 26, and 32 weeks in mouse, rat, and cynomolgus monkey, respectively. "
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