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rhamnazin

has both antiangiogenic and antineoplastic activities

Networked: 10 relevant articles (3 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavonols: 321
        rhamnazin: 10
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavonols: 321
        rhamnazin: 10

Experts

1.	Shao, Yi: 2 articles (07/2018 - 03/2015)
2.	Yu, Yao: 2 articles (07/2018 - 03/2015)
3.	Du, Yanli: 1 article (01/2022)
4.	Sa, Qire: 1 article (01/2022)
5.	Yang, Boxiao: 1 article (01/2022)
6.	Zhang, Rui: 1 article (01/2022)
7.	Lin, Chaozhan: 1 article (01/2021)
8.	Liu, Fangle: 1 article (01/2021)
9.	Lu, Zenghui: 1 article (01/2021)
10.	Ma, Yunxia: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 03/20/2015 - "In this study, we described a novel VEGFR2 inhibitor, rhamnazin, which inhibits tumor angiogenesis and growth. " 03/20/2015 - "Oral administration of rhamnazin at a dose of 200 mg/kg/day could markedly inhibited human tumor xenograft growth and decreased microvessel densities (MVD) in tumor sections. " 09/13/2022 - "We uncovered that rhamnazin exerted its anti-cancer property via reducing cell proliferation and invasion in hepatocellular carcinoma (HCC) cells. " 05/20/2023 - "Rhamnazin Enhanced Anti-Tumor Efficacy of Anti-PD-1 Therapy for Lung Cancer in Mice through Inhibition of PD-L1 Expression." 05/20/2023 - "These data suggest that rhamnazin enhances anti-tumor effect of anti-PD-1 therapy for lung cancer in mice via inhibition of PD-L1 expression."
2.	Lung Neoplasms (Lung Cancer) 05/20/2023 - "This study aims to investigate whether the anti-angiogenic agent rhamnazin enhances the efficacy of anti-PD-1 therapy in lung cancer. " 05/20/2023 - "Rhamnazin Enhanced Anti-Tumor Efficacy of Anti-PD-1 Therapy for Lung Cancer in Mice through Inhibition of PD-L1 Expression." 05/20/2023 - "These data suggest that rhamnazin enhances anti-tumor effect of anti-PD-1 therapy for lung cancer in mice via inhibition of PD-L1 expression."
3.	Inflammation (Inflammations) 01/01/2022 - "Rhamnazin Ameliorates Traumatic Brain Injury in Mice via Reduction in Apoptosis, Oxidative Stress, and Inflammation." 07/24/2018 - "Rhamnazin attenuates inflammation and inhibits alkali burn-induced corneal neovascularization in rats." 01/01/2017 - "ANTIOXIDANT AND ANTI-INFLAMMATORY EFFECTS OF RHAMNAZIN ON LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY AND INFLAMMATION IN RATS." 06/27/2022 - "The Impact of Quercetin and Its Methylated Derivatives 3-o-Methylquercetin and Rhamnazin in Lipopolysaccharide-Induced Inflammation in Porcine Intestinal Cells."
4.	Acute Lung Injury 01/01/2017 - "The antioxidative and anti-inflammatory properties rhamnazin were tested for protection against the acute lung injury. " 01/01/2017 - "ANTIOXIDANT AND ANTI-INFLAMMATORY EFFECTS OF RHAMNAZIN ON LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY AND INFLAMMATION IN RATS."
5.	Traumatic Brain Injuries (Traumatic Brain Injury) 01/01/2022 - "Rhamnazin Ameliorates Traumatic Brain Injury in Mice via Reduction in Apoptosis, Oxidative Stress, and Inflammation."

Related Drugs and Biologics

1.	Alkalies
2.	Quercetin
3.	Lipopolysaccharides
4.	ErbB Receptors (EGF Receptor)
5.	Granzymes (Granzyme)
6.	Luteolin
7.	Mitogen-Activated Protein Kinases
8.	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)
9.	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)
10.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration