Cyclophilin C

A peptidyl-prolyl cis-trans isomerase and member of the cyclophilin family. It catalyzes the cis-trans isomerization of imide-like peptide bonds that occur between PROLINE and other amino acids to facilitate PROTEIN FOLDING.

Also Known As:

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Alfonso, Amparo: 2 articles (01/2022 - 01/2019)
2.	Alonso, Eva: 2 articles (01/2022 - 01/2019)
3.	Bayón, Jeremías: 2 articles (01/2022 - 01/2019)
4.	González-Juanatey, Carlos: 2 articles (01/2022 - 01/2019)
5.	Santás-Álvarez, Melisa: 2 articles (01/2022 - 01/2019)
6.	Testa-Fernández, Ana: 2 articles (01/2022 - 01/2019)
7.	Imai, Hideaki: 2 articles (06/2011 - 03/2005)
8.	Saito, Nobuhito: 2 articles (06/2011 - 03/2005)
9.	Abellás-Sequeiros, Rosa A: 1 article (01/2022)
10.	Botana, Luis: 1 article (01/2022)

Related Diseases

1.	Coronary Artery Disease (Coronary Atherosclerosis) 05/19/2023 - "Our study revealed a significant association between acute and chronic coronary artery disease with increased levels of Cyclophilin C. " 05/19/2023 - "The inclusion criteria were any randomized control trials or controlled observational studies that measured the levels of Cyclophilin C in Coronary Artery disease patients and healthy controls. " 01/01/2019 - "High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease." 05/19/2023 - "We aimed to perform a meta-analysis to investigate the value of Cyclophilin C as a diagnostic and prognostic biomarker in Coronary Artery Disease. " 05/19/2023 - "Cyclophilin C as a Novel Diagnostic and Prognostic Biomarker of Coronary Artery Diseases. "
2.	Neoplasms (Cancer) 07/24/2009 - "Cyclophilin C-associated protein (CyCAP) has been described to down-modulate endotoxin signaling in colorectal murine mucosa and is a murine orthologue of the tumor-associated antigen 90 K (TAA90K)/mac-2-binding protein. " 04/01/2000 - "We report on the basis of partial protein and cDNA sequence information, that the 100-kDa glycoprotein detected by MAb 1H9 is identical to the 90-kDa glycoprotein variably known as tumor-associated antigen 90K (TAA90K), Mac-2 binding protein, and cyclophilin C-associated protein. "
3.	Ischemia 06/23/2011 - "Cyclophilin C-associated protein (CyCAP) was proposed to be an endogenous equivalent of CsA; CsA- and CyCAP-targeting protein cyclophilin C have attracted extensive attention regarding their ischemia-alleviating mechanisms. " 03/01/2005 - "Expressions of CyCAP and cyclophilin C mRNA in a rat middle cerebral artery (MCA) occlusion ischemia model were investigated by Northern blotting and in situ hybridization. "
4.	Carcinogenesis 07/24/2009 - "Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane."
5.	Dyslipidemias (Dyslipidemia) 01/01/2023 - "The multivariate analysis strengthens the predictive value for coronary artery disease presence of cyclophilin A (>8.2 ng/mL) and cyclophilin C (>17.5 pg/mL) along with the cardiovascular risk factors tobacco, hypertension, dyslipidemia, and high glucose and cholesterol levels. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Biomarkers (Surrogate Marker)
3.	Carrier Proteins (Binding Protein)
4.	Antigens
5.	Osteopontin
6.	Cyclophilin A
7.	Complementary DNA (cDNA)
8.	Cyclins
9.	Thrombin
10.	Messenger RNA (mRNA)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)