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Immunophilins

Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.
Also Known As:
Neurophilin; Neurophilins; Immunophilin
Networked: 165 relevant articles (6 outcomes, 22 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Galigniana, Mario D: 6 articles (01/2021 - 05/2004)
2. Romano, Maria Fiammetta: 5 articles (01/2020 - 08/2005)
3. Romano, Simona: 5 articles (01/2020 - 08/2005)
4. Burnett, Arthur L: 5 articles (07/2009 - 05/2005)
5. Matsuoka, Nobuya: 4 articles (06/2012 - 02/2005)
6. Yamaji, Takayuki: 4 articles (06/2012 - 02/2005)
7. Yamazaki, Shunji: 4 articles (06/2012 - 02/2005)
8. Sezen, Sena F: 4 articles (07/2009 - 06/2007)
9. Romano, M F: 3 articles (05/2018 - 01/2011)
10. Romano, S: 3 articles (05/2018 - 01/2011)

Related Diseases

1. Ischemia
2. Nervous System Diseases (Neurological Disorders)
3. Traumatic Brain Injuries (Traumatic Brain Injury)
4. Spinal Cord Injuries (Spinal Cord Injury)
5. Erectile Dysfunction

Related Drugs and Biologics

1. Ligands
2. Cyclosporine (Ciclosporin)
3. Immunosuppressive Agents (Immunosuppressants)
4. Tacrolimus (Prograf)
5. Glutathione (Reduced Glutathione)
6. FK1706
7. Tacrolimus Binding Proteins (FKBP)
8. tacrolimus binding protein 4 (FKBP52)
9. Tacrolimus Binding Protein 1A (FKBP12)
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Rewarming
4. Organ Transplantation
5. Corneal Transplantation (Keratoplasty)