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Isomerases

A class of enzymes that catalyze geometric or structural changes within a molecule to form a single product. The reactions do not involve a net change in the concentrations of compounds other than the substrate and the product.(from Dorland, 28th ed) EC 5.
Also Known As:
Isomerase
Networked: 463 relevant articles (8 outcomes, 41 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Flaumenhaft, Robert: 9 articles (01/2022 - 03/2014)
2. Furie, Bruce: 8 articles (01/2019 - 10/2012)
3. Matsumoto, Isao: 7 articles (04/2012 - 08/2002)
4. Sumida, Takayuki: 7 articles (04/2012 - 08/2002)
5. Thomas, James L: 7 articles (05/2011 - 11/2002)
6. Lu, Kun Ping: 6 articles (01/2019 - 02/2006)
7. Gibbins, Jonathan M: 5 articles (11/2021 - 04/2007)
8. Moreno-Sánchez, Rafael: 5 articles (11/2020 - 05/2014)
9. Rodríguez-Enríquez, Sara: 5 articles (11/2020 - 05/2014)
10. Zhou, Xiao Zhen: 5 articles (01/2019 - 05/2015)

Related Diseases

1. Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
2. Neoplasms (Cancer)
3. Arthritis (Polyarthritis)
4. Neoplasm Metastasis (Metastasis)
5. Hypoxia (Hypoxemia)
01/01/2018 - "Chronic hypobaric hypoxia caused a substantial increase in protein oxidation and exhibited a greater activation of ER chaperones, glucose-regulated protein-78 (GRP-78) and protein disulphide isomerase (PDI) till 14d of CHH. "
06/17/2002 - "Transfection with hypoxia-inducible factor-1alpha and dominant-negative hypoxia-inducible factor-1alpha enhanced and suppressed the expression of autocrine motility factor/phosphohexase isomerase/neuroleukin mRNA and the random motility, respectively. "
06/17/2002 - "These results suggest that hypoxia may promote the metastatic potential of cancer cells through the enhanced autocrine motility factor/phosphohexase isomerase/neuroleukin mRNA expression and that the disruption of the hypoxia-inducible factor-1 pathway may be an effective treatment for metastasis."
10/25/2011 - "Considering that acute inflammation may affect expression of molecular reference genes, we evaluated the expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and prolylpeptidyl isomerase A (PPIA) in the air pouch membrane during a complete time course of urate crystal inflammation and correlated the results with expression of interleukin (IL)-1β and hypoxia inducible factor (HIF)-1α. "
10/24/2011 - "In order to determine the most stable and suitable reference genes for the study of rat carotid body during development, six commonly used reference genes, β-actin, RPII (RNA polymerase II), PPIA (peptidyl-proyl-isomerase A), TBP (TATA-box binding protein), GAPDH, and 18s rRNA, were evaluated in two age groups (P0-1 and P14-16) under three environmental oxygen conditions (normoxia, chronic hypoxia and chronic hyperoxia) using the three most commonly used software programs, geNorm, NormFinder and BestKeeper. "

Related Drugs and Biologics

1. Glucose (Dextrose)
2. Proteins (Proteins, Gene)
3. Phosphates (Orthophosphate)
4. Cyclophilins (Cyclophilin)
5. Cyclophilin A
6. Messenger RNA (mRNA)
7. Antiviral Agents (Antivirals)
8. Therapeutic Uses
9. Linoleic Acid (Linoleate)
10. Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)

Related Therapies and Procedures

1. Kidney Transplantation
2. Renal Dialysis (Hemodialysis)
3. Highly Active Antiretroviral Therapy (HAART)
4. Therapeutics
5. Ovariectomy (Oophorectomy)