Biological Markers (Surrogate Marker)

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18564 relevant articles (673 outcomes, 3031 trials/studies) found for this Bio-Agent

Description: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

Also Known As:

Surrogate Marker; Surrogate Endpoint; Surrogate Markers; Surrogate End Points; Biological Marker; Biochemical Marker; Biologic Marker; Biologic Markers; Biomarkers; Clinical Marker; Immune Marker; Immune Markers; Immunologic Marker; Laboratory Marker; Marker, Biochemical; Marker, Biological; Marker, Clinical; Marker, Immunologic; Marker, Laboratory; Marker, Serum; Marker, Surrogate; Serum Marker; Surrogate End Point; Surrogate Endpoints; Viral Marker; End Point, Surrogate; End Points, Surrogate; Endpoint, Surrogate; Endpoints, Surrogate; Marker, Biologic; Marker, Immune; Marker, Viral; Markers, Biologic; Markers, Immune; Biochemical Markers; Clinical Markers; Immunologic Markers; Laboratory Markers; Markers, Biochemical; Markers, Biological; Markers, Clinical; Markers, Immunologic; Markers, Laboratory; Markers, Serum; Markers, Surrogate; Markers, Viral; Serum Markers; Viral Markers

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Poynard, Thierry: 18 articles (09/2008 - 09/2002)
2.	Morrow, David A: 17 articles (09/2008 - 07/2003)
3.	Ratziu, Vlad: 15 articles (09/2008 - 09/2002)
4.	Srivastava, Sudhir: 15 articles (05/2008 - 06/2002)
5.	Imbert-Bismut, Françoise: 13 articles (09/2008 - 09/2002)
6.	Rifai, Nader: 13 articles (05/2008 - 08/2002)
7.	Messous, Djamila: 12 articles (09/2008 - 08/2003)
8.	Diamandis, Eleftherios P: 11 articles (10/2008 - 05/2002)
9.	Christenson, Robert H: 11 articles (03/2008 - 08/2002)
10.	Blennow, Kaj: 11 articles (01/2008 - 06/2003)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1996 - "Short-term clinical trials then determine optimal dosing and characterize the efficacy of the best agents against intermediate biomarkers of cancer" 05/01/2001 - "By exploring the status of relevant biomarkers, these approaches become effective in evaluating exposure and susceptibility and show enormous potential for elucidating mechanisms of carcinogenesis and the effect of risk factors in cancer" 01/01/1983 - "A wide range of new multidisciplinary biotechnologies applied to tumor biomarkers promises additional and improved assays for highly sensitive and specific detections of human neoplasia" 08/30/2006 - "These easily fabricated SWNT immunosensors show excellent promise for clinical screening of cancer biomarkers and point-of-care diagnostics." 01/01/2007 - "Carefully designed ongoing studies are expected to generate data on whether folate-related biomarkers could be used to identify subjects who are at risk of developing cervical cancer and whether folate supplementation will be beneficial in preventing cervical cancer in women exposed to HR-HPV." Order ALL the reference details at left...
2.	Inflammation 05/01/2007 - "Moreover, several studies in different species have shown that limited energy intake is associated with less inflammation, improved biomarkers of health and a marked increase in longevity" 04/01/2005 - "Both patients demonstrated rapid improvement in clinical symptoms and laboratory markers of inflammation" 12/01/2002 - "However, it is not clear whether inhaled glucocorticosteroids (GCSs) provide greater protection against specific surrogate markers of airways inflammation than other means" 05/01/1995 - "Laboratory markers of inflammation also showed statistically significant change in favor of SSZ" 01/01/2001 - "OBJECTIVE: The purpose of this study was to determine whether analysis of the constituents of induced sputum could be used to document the efficacy of a nurse-delivered patient education intervention and whether changes in the biological markers of inflammation in sputum would correlate with improvements in pulmonary function and symptoms" Order ALL the reference details at left...
3.	Infection 01/01/2000 - "RESULTS: The patient made a rapid clinical recovery, and biochemical markers of infection improved promptly" 05/01/1992 - "New assays for quantitative determination of viral markers in management of chronic hepatitis B virus infection." 08/01/2001 - "Disappearance of viraemia does not necessarily imply clearance of GBV-C/HGV but may be due to a change of GBV-C(HGV into a state of persistence without positive laboratory markers of the infection" 11/15/2008 - "HPV has also been investigated as an NMSC risk factor in epidemiologic studies, although findings vary across studies that used different biomarkers of HPV infection in normal tissues" 10/01/2008 - "Ultimately, this study provides support for utilizing in vitro microarray gene expression profiling in human PBMCs to identify biomarkers of infection and predict in vivo immune responses to infectious agents." Order ALL the reference details at left...
4.	Prostatic Neoplasms (Prostate Cancer) 01/18/2008 - "Future studies on the identified differentially expressed genes and signaling pathways may be helpful in understanding the biology of prostate cancer progression and prove useful in developing novel prognostic biomarkers and therapy for androgen-refractory prostate cancer." 06/01/2006 - "Prostate cancer has been a focus of many such studies with the promise of improved care to patients via biomarkers derived from these proteomic approaches" 11/01/2004 - "Evidence-based medical perspectives: the evolving role of PSA for early detection, monitoring of treatment response, and as a surrogate end point of efficacy for interventions in men with different clinical risk states for the prevention and progression of prostate cancer." 07/01/2004 - "There is a need for improved biomarkers for detecting prostate cancer" 06/02/2004 - "Improved biomarkers for prostate cancer: a definite need." Order ALL the reference details at left...
5.	Disease Progression 01/01/1991 - "These activities generate stabilization or improvement in three important surrogate markers of HIV disease progression" 04/01/2008 - "Potential clinical applications of biomarkers are found in improved diagnosis, monitoring of disease progression and assessment of therapeutic correction" 08/01/2004 - "As well as disclosing new therapeutic targets and preclinical and clinical data for drugs in development, several presentations discussed the development of surrogate markers and imaging techniques to monitor disease progression and therapeutic efficacy." 03/01/1993 - "We propose that serial quantitative measurement of saccade performance is a useful clinical marker of the rate of disease progression against which the efficacy of treatments may be tested." 08/01/2008 - "Although these available predictive models provide a reasonable assessment of patients' risks of disease progression, the accuracy of these models may further be improved via the incorporation of molecular prognostic biomarkers" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Biological Markers (Surrogate Marker)
2.	Antigens
3.	Proteins (Proteins, Gene)
4.	DNA (Deoxyribonucleic Acid)
5.	Prostate-Specific Antigen (Semenogelase)
6.	Calcium
7.	C-Reactive Protein
8.	alpha-Fetoproteins (AFP)
9.	Antibodies
10.	Osteocalcin

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Chemoprevention
3.	Therapeutics
4.	Highly Active Antiretroviral Therapy (HAART)
5.	Critical Care

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