HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Ischemia

A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Also Known As:
Ischemias
Networked: 76319 relevant articles (5200 outcomes, 10209 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infarction (Infarctions)
2. Reperfusion Injury
3. Hypoxia (Hypoxemia)
4. Myocardial Infarction
5. Stroke (Strokes)

Experts

1. Won, Moo-Ho: 146 articles (05/2022 - 08/2006)
2. Hwang, In Koo: 134 articles (04/2022 - 11/2002)
3. Stone, Gregg W: 114 articles (03/2022 - 03/2002)
4. Yoo, Ki-Yeon: 99 articles (05/2022 - 04/2004)
5. Zhang, Li: 92 articles (08/2022 - 04/2002)
6. Wang, Wei: 89 articles (10/2022 - 12/2002)
7. Park, Joon Ha: 89 articles (05/2022 - 03/2011)
8. Kim, Dae Won: 85 articles (05/2022 - 06/2004)
9. Lee, Jae-Chul: 78 articles (05/2022 - 07/2006)
10. Zhang, Feng: 77 articles (02/2022 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ischemia:
1. Adenosine Triphosphate (ATP)IBA
2. AntioxidantsIBA
3. Retinaldehyde (Retinal)IBA
4. Proteins (Proteins, Gene)FDA Link
5. Oxygen (Dioxygen)IBA
6. Glucose (Dextrose)FDA LinkGeneric
7. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
8. Adenosine (Adenocard)FDA LinkGeneric
9. CalciumIBA
10. Lactic Acid (Lactate)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Transplantation
3. Induced Heart Arrest (Cardioplegia)
4. Limb Salvage
01/01/1996 - "The limb salvage rate for patients with limb-threatening ischemia was 98% at a mean follow-up of 14 months +/- 7. Technical success and complication rates for percutaneous iliac artery revascularization with use of Wallstents are favorable, symptoms improved in the majority of patients, and excellent secondary patency can be achieved. "
10/16/2020 - "Injecting the CM collected from ps-TNC treated hADSCs into the mouse hindlimb ischemia model (ps-TNC-CM group) showed significantly improved angiogenesis in the lesions, with improved limb salvage and decreased muscle degeneration compared to the group injected with CM collected from normal hADSCs (CM group). "
04/01/2014 - "Compared with injection of either monolayer culture CM or human ADSC, injection of spheroid culture CM to an ischemic region in mice significantly enhanced endothelial cell growth, CD34(+)/PTPRC(-) (endothelial progenitor) cell mobilization from bone marrow, and bone marrow cell homing to the ischemic region, resulting in improved blood vessel density, limb salvage, and blood perfusion in a mouse hindlimb ischemia model. "
11/01/2004 - "When injected into the hind muscles in immunodeficient SCIDbg mice subjected to unilateral ischemia, a low number (10(3)) of CD34+KDR+ cells improved limb salvage and hemodynamic recovery better than a larger dosage (10(4)) of CD34+KDR- cells. "
11/01/2020 - "Bypass to the descending genicular artery, although underutilized, is an effective option and increases the possibility of limb salvage in the management of chronic limb-threatening ischemia."
5. Surgical Amputation (Amputations)