Abstract |
In order to compare the efficacy of immediate intravenous oxytocin administration and intracervical prostaglandin E2 gel application in premature rupture of membranes with unfavorable cervices at term, 45 term pregnant patients with premature rupture of membranes were randomized into two groups. Twenty women received immediate intravenous oxytocin after cleansing enema while the rest were treated with intracervical prostaglandin E2 gel. Means of maternal age, gestational age, Bishop score at admission and the rates of nulliparity did not show any significant differences between the two groups (p > 0.05). The mean rupture to delivery time was 12.6 +/- 4.4 hours in the oxytocin group and 16.5 +/- 4.5 hours in the prostaglandin group (p < 0.01). Mean birth weights and Apgar scores were insignificant. Cesarean section rates were 24% in the oxytocin group and 5% in the other (p < 0.05). No infectious morbidity was seen in any case. In conclusion, although delivery is delayed with the intracervical prostaglandin approach, cesarean section rate is lowered without an increase in infectious morbidity.
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Authors | T Bilgin, M Kadioğlu, V Yildirim, C Cengiz |
Journal | Clinical and experimental obstetrics & gynecology
(Clin Exp Obstet Gynecol)
Vol. 25
Issue 1-2
Pg. 46-8
( 1998)
ISSN: 0390-6663 [Print] Singapore |
PMID | 9743881
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Gels
- Oxytocics
- Oxytocin
- Dinoprostone
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Topics |
- Administration, Topical
- Adult
- Dinoprostone
(administration & dosage, therapeutic use)
- Female
- Fetal Membranes, Premature Rupture
(therapy)
- Gels
- Humans
- Injections, Intravenous
- Oxytocics
(administration & dosage, therapeutic use)
- Oxytocin
(administration & dosage, therapeutic use)
- Pregnancy
- Treatment Outcome
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