[Study on the sclerosing agent for the treatment of simple renal cysts].

Abstract

BACKGROUND:

The objective of this study is to evaluate the sclerosing agents for simple renal cysts.

METHODS:

Thirty-three renal cysts of 30 patients were treated by injection of sclerosing agents with the guidance of ultrasonography. Among them, 22 were treated with ethanol, and 11 with minocycline-hydrochloride (MINO).

RESULTS:

Clinical efficacy rates and volume reduction rates in each treatment group of ethanol or MINO, were 100% and 90.9%, and 91.2 +/- 13.1% (mean +/- SD) and 83.2 +/- 28.5%, respectively. Although several complications including pain and intoxication were observed in ethanol (47.4%), no complications were observed in MINO.

CONCLUSION:

The instillation of MINO into renal cysts is an effective, safe and simple treatment. It is thought that it can be the first choice of treatment for simple renal cysts.

• Authors: H Akiyama, T Ichikawa, A Nagai, M Tsugawa, T Tsushima, H Kumon, H Ohmori
• Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology (Nihon Hinyokika Gakkai Zasshi) Vol. 87 Issue 12 Pg. 1277-80 (Dec 1996) ISSN: 0021-5287 [Print] Japan
• PMID: 8997074 (Publication Type: Clinical Trial, English Abstract, Journal Article, Review)

Chemical References

• Sclerosing Solutions
• Ethanol
• Minocycline

Topics

• Adult
• Aged
• Ethanol (adverse effects, therapeutic use)
• Female
• Humans
• Kidney Diseases, Cystic (drug therapy)
• Male
• Middle Aged
• Minocycline (therapeutic use)
• Sclerosing Solutions (therapeutic use)