Reaction rate in cats vaccinated with a new controlled-titer feline panleukopenia-rhinotracheitis-calicivirus-Chlamydia psittaci vaccine.

Abstract

The safety profile of a new controlled-titer feline panleukopenia-rhinotracheitis-calicivirus-Chlamydia psittaci vaccine was compared to that of a currently-marketed vaccine. Of particular interest were delayed reactions (previously unreported in the literature in felines) occurring 7 to 21 days after vaccination, and the effect of concurrent vaccinations and cat age on the delayed reaction rate. Nineteen hundred twenty-four doses of the new vaccine and 364 doses of the comparison vaccine were administered in 42 participating veterinary practices. The postvaccination evaluation period was 21 days. Reactions (anaphylaxis, short- and long-term lethargy, inappetence, pain, upper respiratory inflammation, delayed fever, anorexia, and miscellaneous events) were reported in 3.33% of cats receiving the controlled-titer vaccine and in 3.02% of cats receiving the comparison vaccine. The difference was not statistically significant (P = 0.45). Reaction rate of the controlled-titer vaccine and that of the vaccine currently accepted by veterinarians appear to be equivalent.

• Authors: R M Starr
• Journal: The Cornell veterinarian (Cornell Vet) Vol. 83 Issue 4 Pg. 311-23 (Oct 1993) ISSN: 0010-8901 [Print] United States
• PMID: 8306654 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Bacterial Vaccines
• Vaccines, Attenuated
• Vaccines, Combined
• Viral Vaccines

Topics

• Age Factors
• Anaphylaxis (chemically induced, veterinary)
• Animals
• Bacterial Vaccines (adverse effects, immunology)
• Caliciviridae Infections (prevention & control, veterinary)
• Calicivirus, Feline (immunology)
• Cat Diseases (prevention & control)
• Cats
• Chlamydophila psittaci (immunology)
• Feline Panleukopenia (prevention & control)
• Feline Panleukopenia Virus (immunology)
• Female
• Herpesviridae (immunology)
• Herpesviridae Infections (prevention & control, veterinary)
• Hypersensitivity, Delayed (chemically induced, veterinary)
• Male
• Psittacosis (prevention & control, veterinary)
• Vaccination (adverse effects, veterinary)
• Vaccines, Attenuated (adverse effects, immunology)
• Vaccines, Combined (adverse effects, immunology)
• Viral Vaccines (adverse effects, immunology)