[Clinical studies on cefmetazole in respiratory infections].

Abstract

Cefmetazole (CMZ) was used for the treatment of respiratory infections in 10 cases; six cases of bronchopneumonia, 2 cases of acute exacerbation of chronic pulmonary emphysema or bronchitis disease, 1 case of acute exacerbation of chronic respiratory failure and 1 case of lung abscess. CMZ was administered by intravenous drip infusion at a daily dose of 2 to 4 g for 5 to 24 days. Intramuscular injection of gentamicin was combined in 2 cases. Clinical results were as follows; excellent in 6 cases, good in 2 cases, fair in 1 case and poor in 1 case. As to the side effects of the drug, allergic reaction with fever and eosinophilia was observed in 1 case. This side effect disappeared immediately after cessation of CMZ. In view of the above, CMZ may be considered to be a clinically useful antibiotic against respiratory infections.

• Authors: S Harada, M Kido, A Kajiki, Y Nakajima, A Kuroiwa
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 35 Issue 12 Pg. 2779-84 (Dec 1982) ISSN: 0368-2781 [Print] Japan
• PMID: 6963593 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Cephalosporins
• Cephamycins
• Cefmetazole

Topics

• Adult
• Aged
• Cefmetazole
• Cephalosporins (therapeutic use)
• Cephamycins (administration & dosage, adverse effects, therapeutic use)
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Respiratory Tract Infections (drug therapy)