Bacitracin therapy in antibiotic-associated pseudomembranous colitis.

Abstract

Two patients with antibiotic-associated pseudomembranous colitis, and stool positive for Clostridium difficile cytotoxin were successfully treated with oral bacitracin. One patient had previously suffered two relapses of pseudomembranous colitis following successful treatment with vancomycin and one patient was allergic to vancomycin. Bacitracin appears to be a reasonable choice to treat patients with antibiotic-associated colitis who are allergic to vancomycin. Further studies comparing vancomycin and bacitracin are needed.

• Authors: F J Tedesco
• Journal: Digestive diseases and sciences (Dig Dis Sci) Vol. 25 Issue 10 Pg. 783-4 (Oct 1980) ISSN: 0163-2116 [Print] United States
• PMID: 6903494 (Publication Type: Case Reports, Comparative Study, Journal Article)

Chemical References

• Cephalosporins
• Bacitracin
• Vancomycin
• Ampicillin

Topics

• Adult
• Ampicillin (therapeutic use)
• Bacitracin (therapeutic use)
• Cephalosporins (therapeutic use)
• Clostridium (drug effects)
• Clostridium Infections (drug therapy)
• Enterocolitis, Pseudomembranous (drug therapy, etiology)
• Female
• Humans
• Male
• Penicillin Resistance
• Urinary Tract Infections (drug therapy, microbiology)
• Vancomycin (therapeutic use)