HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Bacitracin (Baci-Rx)

A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)

Also Known As:

Baci-Rx; Baciguent; A.L. Labs Brand of Bacitracin Zinc Salt; Ak-Tracin; Akorn Brand of Bacitracin; Altracin; Baci-IM; Bacitin; Bacitracin Zinc; Bacitracin Zinc Complex; Bacitracine Martinet; Ciba Vision Brand of Bacitracin; Dioptic Brand of Bacitracin; Lee Brand of Bacitracin; McNeil Brand of Bacitracin; Ocu-Tracin; Ocumed Brand of Bacitracin; Pharma Tek Brand of Bacitracin; Pharmascience Brand of Bacitracin; Reed & Carnrick Brand of Bacitracin; Topitracin; Zeba-Rx; Zinc Bacitracin; Ak Tracin; Baci IM; Baci Rx; Bacitracin Akorn Brand; Bacitracin Dioptic Brand; Bacitracin Lee Brand; Bacitracin McNeil Brand; Bacitracin Pharmascience Brand; Bacitracin, Zinc; Martinet, Bacitracine; Ocu Tracin; OcuTracin; Zeba Rx; Zinc, Bacitracin

Networked: 371 relevant articles (31 outcomes, 27 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Beckman, Joshua M: 2 articles (12/2015 - 12/2015)
2.	Tetreault, Lisa L: 2 articles (12/2015 - 12/2015)
3.	Amankwah, Ernest K: 2 articles (12/2015 - 12/2015)
4.	Tuite, Gerald F: 2 articles (12/2015 - 12/2015)
5.	Perlman, Sharon A: 1 article (12/2015)
6.	Rood, Julian I: 1 article (11/2015)
7.	Du, Xiang-Dang: 1 article (11/2015)
8.	Seemann, Torsten: 1 article (11/2015)
9.	Han, Xiaoyan: 1 article (11/2015)
10.	Yan, Xu-Xia: 1 article (11/2015)

Related Diseases

1.	Weight Gain 07/01/1977 - "The addition of zinc bacitracin significantly improved (P less than 0.01) the parameters of weight gain, feed conversion, and pigmentation." 08/01/1983 - "Supplementing a soybean meal and corn-based diet with a level of 55 ppm of bacitracin did not significantly affect weight gain, feed efficiency, or numbers of C. " 05/01/2015 - "Birds given zinc bacitracin, yeast cell wall extract, or salinomycin had improved weight gain and livability when compared to control birds given no additives. " 01/01/1985 - "Flavophospholipol (flavofarm-NIHFI) was given at rates of 0, 4, 8, 12, and 16 ppm. The method of positive control check was employed--a group which was offered zinc-bacitracin--(bacifarmin) at 30 ppm. Under the effect of flavophospholipol the weight gain was 2.2 to 21.2 per cent higher, and the weight of the liver rose by 1.4-23.1 per cent. " 08/01/1983 - "Supplementing a soybean protein and sucrose-based diet with 2.2, 11, and 55 ppm of bacitracin resulted in significant improvements in weight gain and feed efficiency of chicks fed the higher levels. "
2.	Wounds and Injuries (Trauma) 12/01/2015 - "CONCLUSIONS To the authors' knowledge, this is the first study to systematically analyze the potential complications of concentrated bacitracin powder applied to surgical wounds. " 12/01/2015 - "The surgeon applied bacitracin powder to all shunt wounds prior to closure between 2008 and 2013, whereas no antibiotic powder was applied to wounds prior to 2008. " 12/01/2015 - "As a result of these findings, the corresponding author began systematically applying concentrated bacitracin powder directly to wounds during shunt surgery more than 5 years ago. " 12/01/2015 - "RESULTS A total of 597 patients were reviewed in the analysis: 389 underwent surgery without bacitracin powder and 208 had concentrated bacitracin powder applied to the wounds prior to closure. " 12/01/2015 - "Data were stratified by typical demographic, medical, and surgical variables, including whether bacitracin powder was applied to wounds prior to closure. "
3.	Infection 01/01/1985 - "We conclude that pretreatment of a hydrocephalic shunt tubing with an aqueous bacitracin solution before its implantation may help to reduce the postoperative shunt infections due to direct contamination of the shunt at the time it is inserted." 12/01/2015 - "Bacitracin powder use was associated with a reduced risk of shunt infection in univariate analysis (HR 0.11, 95% CI 0.03-0.34, p = 0.0002) and also in multivariate analysis (HR 0.12, 95% CI 0.04-0.41, p = 0.0006) when controlling for covariates that were associated with infection from the univariate analysis. " 12/01/2015 - "Procedures performed before the use of concentrated bacitracin powder was instituted resulted in a 13% infection rate, whereas procedures performed after systematic use of bacitracin powder had been adopted experienced a 1% infection rate. " 12/01/2015 - "The association between bacitracin powder use and shunt infection was estimated using hazard ratios (HRs) and 95% CIs from Cox proportional hazard regression models. " 12/01/2015 - "A single surgeon's cranial shunt surgery experience, equally divided between periods during which antibiotic powder was and was not applied, was studied to assess the effect of concentrated bacitracin powder application on shunt infection rates. "
4.	Burns 03/01/1958 - "The problem of infection in burns by resistant micro-organisms with a note on the use of bacitracin." 04/01/1994 - "To investigate this hypothesis in a burn model, a study was performed in which two groups of C3H-HeN mice underwent a different period of intestinal overgrowth by a single neomycin-resistant (NR) Escherichia coli strain after oral neomycin-bacitracin treatment. " 05/01/1960 - "Local therapy of burns with a neomycin-bacitracin spray powder." 05/01/2009 - "Ten of these patients had been treated with Aquacel Ag Hydrofiber dressing and 10 were treated with conventional Xeroflo gauze with Bacitracin Zinc ointment, the institutional standard of care for nonoperative partial-thickness burn wounds. " 01/01/2010 - "Rats were randomly allocated to four groups after local burn development: Group 1; rats were left to secondary healing without treatment, Group 2; a dose of 10 mg/kg montelukast was given by gastric gavage once a day for 10 days, Group 3; rats were treated with topical pomade (bacitracin neomycin sulphate), and Group 4; rats were treat with a combination of topical antibiotic and montelukast (10 mg/kg were given by gastric gavage once a day for 10 days). "
5.	Body Weight (Weight, Body) 03/01/1999 - "2. The maximum improvement in body weight over the controls was 10.8% with both additives in the diet but the use of bacitracin alone induced a 9.1% improvement. " 07/01/1991 - "No significant differences were associated with the feeding of bacitracin methylene disalicylate among body weight or mortality data summarized at 8 and 23 wk. Eight-week feed efficiency was also not affected. " 07/01/1986 - "Regression of body weight and feed utilization on dietary levels of zinc bacitracin indicated that each milligram of zinc bacitracin in the diet increased the 49-day weight of broiler chickens by .92 g and reduced the feed required per gram of gain by .0012 g." 08/01/1983 - "A level of 55 ppm of bacitracin added to the practical diet had no significant effect on body weight, intestinal weight, or liver weight. " 08/01/1983 - "Six experiments were conducted to evaluate the effects of diet, bacitracin, and body weight restrictions on the intestine of the broiler chick. "

Related Drugs and Biologics

1.	Polymyxin B (Aerosporin)
2.	Neomycin
3.	Vancomycin
4.	Penicillins (Penicillin)
5.	Silver Sulfadiazine (SSD)
6.	Bambermycins (Bambermycin)
7.	Virginiamycin
8.	Lincomycin (Lincocin)
9.	Chlortetracycline (Aureomycin)
10.	Oxytetracycline (Terramycin)

Related Therapies and Procedures

1.	First Aid (Aids, First)
2.	Oral Administration
3.	Transplants (Transplant)
4.	Aftercare (After-Treatment)
5.	Radiotherapy