Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
Also Known As:
AB-Vancomycin; Abbott Brand of Vancomycin Hydrochloride; Azupharma Brand of Vancomycin Hydrochloride; Chiesi Brand of Vancomycin Hydrochloride; Combino Brand of Vancomycin Hydrochloride; Dakota Brand of Vancomycin Hydrochloride; Diatracin; Dista Brand of Vancomycin Hydrochloride; Eli Lilly Brand of Vancomycin Hydrochloride; Hexal Brand of Vancomycin Hydrochloride; Lilly Brand of Vancomycin Hydrochloride; MIP Brand of Vancomycin Hydrochloride; Norman Brand of Vancomycin Hydrochloride; VANCO-cell; Vanco Azupharma; Vanco-saar; Vancocin; Vancocin HCl; Vancocine; Vancomicina Abbott; Vancomicina Chiesi; Vancomicina Combino Phar; Vancomicina Norman; Vancomycin Hexal; Vancomycin Hydrochloride; Vancomycin Lilly; Vancomycin Phosphate (1:2); Vancomycin Phosphate (1:2), Decahydrate; Vancomycin Sulfate; Vancomycin-ratiopharm; Vancomycine Dakota; cell pharm Brand of Vancomycin Hydrochloride; curasan Brand of Vancomycin Hydrochloride; ratiopharm Brand of Vancomycin Hydrochloride; Hydrochloride, Vancomycin; Sulfate, Vancomycin
Networked: 6093 relevant articles (724 outcomes, 751 trials/studies)

Relationship Network

Drug Context: Research Results


1. Rybak, Michael J: 39 articles (09/2015 - 04/2002)
2. Sakoulas, George: 31 articles (07/2015 - 05/2003)
3. Corey, G Ralph: 25 articles (12/2015 - 06/2005)
4. Howden, Benjamin P: 19 articles (01/2016 - 02/2004)
5. Fowler, Vance G: 19 articles (04/2015 - 04/2004)
6. Lodise, Thomas P: 18 articles (10/2015 - 04/2002)
7. Kollef, Marin H: 18 articles (01/2014 - 03/2003)
8. Barriere, Steven L: 16 articles (10/2015 - 06/2005)
9. Bayer, Arnold S: 16 articles (07/2015 - 11/2003)
10. Levine, Donald P: 16 articles (01/2015 - 06/2005)

Related Diseases

1. Infection
2. Endocarditis
3. Pneumonia (Pneumonitis)
11/01/2011 - "A prospective cohort study was performed to determine the optimal dose of vancomycin to maintain a serum trough concentration of at least 15 to 20 mg/l and to assess the efficacy of this target vancomycin concentration in the treatment of methicillin-resistant Staphylococcus aureus pneumonia. "
09/01/2009 - "Due to the emergence of vancomycin-intermediate resistance at a fAUC24/MIC of < or = 210, exceeding this exposure breakpoint in ELF may help to guide optimal dosage regimens in the treatment of MRSA pneumonia."
01/01/2004 - "Clinical and pharmacokinetic information was used to determine the following: (i) whether steady-state 24-hour area under the concentration-time curve (AUC24) divided by the MIC (AUC24/MIC) values for vancomycin could be precisely calculated with a software program; (ii) whether the percentage of time vancomycin serum concentrations were above the MIC (%Time>MIC) was an important determinant of vancomycin response; (iii) whether the time to bacterial eradication differed as the AUC24/MIC value increased; (iv) whether the time to bacterial eradication for vancomycin differed compared with other antibacterials at the same AUC24/MIC value; and (v) whether a relationship existed between time to bacterial eradication and time to significant clinical improvement of pneumonia symptoms. "
09/01/2005 - "MRSA pneumonia: better outcome through continuous infusion of vancomycin?"
04/01/2011 - "The objective of this study is to assess the distribution of vancomycin minimum inhibitory concentrations (MICs) in methicillin-resistant Staphylococcus aureus (MRSA) isolates and evaluate the efficacy of vancomycin relative to vancomycin MICs in adult patients with MRSA nosocomial pneumonia. "
4. Bacteremia
5. Peritonitis

Related Drugs and Biologics

1. linezolid (Zyvox)
2. Rifampin (Rifampicin)
3. Anti-Bacterial Agents (Antibiotics)
4. Daptomycin
5. Teicoplanin
6. Gentamicins (Gentamicin)
7. Methicillin (Metin)
8. Penicillins (Penicillin)
9. Metronidazole (Metric)
10. Cefazolin (Ancef)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Catheters
3. Continuous Ambulatory Peritoneal Dialysis (CAPD)
4. Peritoneal Dialysis
5. Transplantation (Transplant Recipients)